Results 61 to 70 of about 5,521,055 (306)
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
STIMULATING ENTREPRENEURSHIP IN THE ROMANIAN EDUCATION SYSTEM [PDF]
Annals of the University of Petrosani: Economics, 2014 Romania is on its way to find and apply the most effective solutions in order to ensure a sustainable economic growth and stable and well paid employment.
DORINA NIȚĂ
doaj
Intercultural perspectives on formal and informal Music learning
DEDiCA, 2011 This paper reviews some of the changes and developments that have occurred in music education over the last decade, following Hargreaves and North’s (2001) international review.
David J. Hargreaves
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Vers un système expert en formation de base
Canadian Journal of EducationL'auteur présente une définition de la formation de base qui implique un modèle interdisciplinaire de référence. Ce modèle, inspiré des travaux de Lonergan (1978) et de Angers (1985), décrit la connaissance selon quatre niveaux d'intégration: niveau ...
Jan Palkiewicz
doaj +6 more sources
Educational Theater: Components And Objectives
العمدة في اللسانيات و تحليل الخطابRegardless of the contexts in which educational theater is employed, whether within educational institutions or in standalone theaters, it is considered one of the most significant methods of modern education.
Souaad Taleb, Hafida Zine
doaj
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Profiling the Educational Value of Computer Games [PDF]
, 2014 There are currently a number of suggestions for educators to include computer games in formal teaching and learning contexts. Educational value is based on claims that games promote the development of complex learning.
Alejandra Recio-Saucedo +7 more
core +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source