Results 31 to 40 of about 260,609 (223)

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Navigating inclusion: understanding social perception, educational opportunity, and challenges for neurodiverse students in Bangladeshi formal education

Frontiers in Education
Neurodiversity movement around the world pushes the society to ensure inclusion in all settings in where societal perspectives play the vital roles for effective changes.
Sabbir Ahmed Chowdhury, Sabbir Ahmed Chowdhury, Mohammad Ashraful Islam, Mohammad Ashraful Islam, Md. Tahmid Anjum Nishat, Md. Tahmid Anjum Nishat, Md. Adnan Nadiv, Nosrat Jahan Ormi   +7 more
doaj   +1 more source

OPPORTUNITIES FOR CONTINUOUS EDUCATIONAL SPACE

Вестник университета, 2020
The space of modern education is voluminous. It is so capacious that it can accommodate any number of different educational systems. On the one hand, these are systems of pre-school, General, and vocational education, which in turn include subsystems of ...
T. Yu. Krotenko
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Educational Opportunities [PDF]

AORN Journal, 2021
  +6 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Justice in Achievement Matters: The Fairness of Educational Opportunities and Active Citizenship

Social Sciences
Unlike existing research which has focused mainly on the effects of educational attainment and curricula on active citizenship, the present article aims to study the relationship of subjective assessment regarding the fairness of people’s educational ...
Pepka Boyadjieva, Petya Ilieva-Trichkova, Valery Todorov   +2 more
doaj   +1 more source

Pursuing Equity in and Through Teacher Education Program Admissions

Education Policy Analysis Archives, 2011
This case study investigated equity in teacher education admissions. Through document analysis and structured interviews with ten past or current members of the admissions committee in a large initial teacher education program in Ontario, we developed an
Ruth Childs, Kathryn Broad, Kelly Gallagher-Mackay, Yael Sher, Kerry-Ann Escayg, Christopher McGrath   +5 more
doaj   +1 more source