Results 61 to 70 of about 945,387 (307)

Teaching Peace – The Need for Teacher Training in Poland to Promote Peace [PDF]

, 2015
The aim of the paper is to stimulate the discussion on peace education and the need of teacher training for peace and multicultural understanding. This paper is organized in two sections: the first section presents the importance of peace education for ...
Leek, Joanna
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Ecosystem of learning with "augmented reality": educational possibilities

Tecnología, Ciencia y Educación, 2016
When we speak about «augmented reality» (AR), we can say that we are in front of an emergent technology that is acquiring a great impulse in the educational area. The technology of the AR offers us different possibilities to move to contexts of formation
Julio Cabero Almenara, Julio Barroso Osuna   +1 more
doaj  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Historical reenactments and commemorations, differences and educational possibilities from Aragon (Spain)

Didattica della storia, 2020
Historical reenactment is a very important and didactic tool. In Aragon, one of the historical regions of Spain, in 2018 were celebrated 57 historical commemoration activities, although many of them are not true reenactments or good living history acts ...
Darío Español Solana, Jesús Gerardo Franco Calvo, José-Manuel González González   +2 more
doaj   +1 more source

Open Education as Disruption: Lessons for Open and Distance Learning from Open Educational Practice [PDF]

, 2016
This paper reflects on what Open and Distance Learning providers might learn from the Open Educational Resources/Practices (OER/OEP) and Massive Open Online Courses (MOOCs).
Macintyre, Ronald
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Utilize Educational Robots to Design Logistic Systems

Applied Sciences
The use of educational robots is new in terms of their utilization for designing logistic systems. The current methodology for designing logistic systems is not directly oriented towards the use of educational robots. This indicates the need to develop a
Jakub Kovalčík, Martin Straka, Justyna Trojanowska   +2 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Posibilidades educativas de la wiki Educational possibilities of wiki

Tecnología en Marcha, 2012
El artículo presenta el recurso wiki como una herramientaflexiblequeaportagrandesposibilidades a la educación. Su principal característica es que permite a un conjunto de usuarios interactuar de forma asincrónica para crear algún tipo de contenido y que ...
Francisco Mora Vicarioli
doaj