Results 41 to 50 of about 427,659 (248)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Innovation Model of Digital Library Management to Enhance Literacy Culture in Senior High Schools

Jurnal Inovasi Pendidikan dan Sains
This study aims to analyze how digital library innovations cultivate a reading culture in senior high schools. The specific objectives are to examine the planning, implementation, evaluation, and management models applied in school-based digital library ...
Noviyanti Noviyanti, Siraj Siraj, Cut Khairani   +2 more
doaj   +1 more source

Flexible vs. rigid dieting in resistance-trained individuals seeking to optimize their physiques: A randomized controlled trial

Journal of the International Society of Sports Nutrition, 2021
Background The purpose of this study was to compare a flexible vs. rigid diet on weight loss and subsequent weight regain in resistance-trained (RT) participants in a randomized, parallel group design.
Laurin Alexandra Conlin, Danielle Trina Aguilar, Gavin Elliot Rogers, Bill I Campbell   +3 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Mapping Teacher’s Readiness to Improve the Government Policy in Implementing Higher-Order Thinking Skills-Based Learning

Qubahan Academic Journal
Recently, there have been many trainings aimed at investigating pedagogical practices among teachers related to HOTS-based teaching in the context of Indonesian education.
Taufiq Lilo Adi Sucipto , Sajidan Sajidan, Muhammad Akhyar, Roemintoyo Roemintoyo   +3 more
doaj   +1 more source

THE DEVELOPMENT OF CAI BASED ANDROID IN SOLAR SYSTEM AND UNIVERSE TOPIC FOR TENTH-GRADE

Geosfera Indonesia, 2019
The aim of the research to generate learning media, thus the media development will assist students to understand the content during the learning process. Besides establishing a product, the manual guide was also arranged.
M Marwiyah, R Rusijono, Fajar Arianto
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Clinical confidence following an interprofessional educational program on eating disorders for health care professionals: a qualitative analysis

Journal of Multidisciplinary Healthcare, 2012
Gunn Pettersen,1 Jan H Rosenvinge,1 Kari-Brith Thune-Larsen,2 Rolf Wynn1,31Faculty of Health Sciences, University of Tromsø, Tromsø, Norway; 2Oslo University Hospital, Oslo, Norway; 3Division of Addictions and Specialized Services ...
Pettersen G, Rosenvinge JH, Thune-Larsen KB, Wynn R   +3 more
doaj  

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source