Results 51 to 60 of about 2,940,980 (314)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

The Chafee Educational and Training Voucher Program: Six States' Experiences [PDF]

open access: yes, 2007
This publication examines how the Chafee educational and training vouchers and other state-based supports for higher education have been working for these young adults.
Maria Garin Jones, Robin Nixon
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Educational Rights of Homeless Children: Creating a Model Program in Illinois [PDF]

open access: yes, 2000
The lack of affordable, permanent housing forces many families to move frequently and results in many children changing schools repeatedly. Such mobility has a devastating impact on the educational opportunities of children experiencing a housing ...
Patricia Nix-Hodes, Rene Heybach
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Trends in the Use of Augmented Reality from Tangible Interfaces in School Learning : A Systematic Literature Review

open access: yesJurnal Paedagogy
This study aims to analyze trends in the use of augmented reality from tangible interfaces in the context of formal and informal education. This study employed a systematic literature review (SLR) method adapted from the PRISMA model.
I Putu Eka Indrawan   +3 more
doaj   +1 more source

Engagement in Authentic Geoscience Research: Evaluation of Research Experiences of Undergraduates and Secondary Teachers [PDF]

open access: yes, 2003
This article examines the effects of a program involving authentic research on the participants' interest in research, career plans, and attitudes on science.
Olga Jarrett, Pamela Burnley
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Beyond One-Size-Fits-All: Mapping the Impact of Educational Technology Tools on Students' Critical Thinking

open access: yesJurnal Edutech Undiksha
The gap between the potential of educational technology tools and students' achievement of critical thinking skills in practice prompted this study.
Zhong Ziyan   +2 more
doaj   +1 more source

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