Results 71 to 80 of about 455,283 (268)

Implementation and Actualization of Human Resource Development Programs to Improve Teacher Professionalism in Junior High Schools in the Hinterland Area of Batam

Jurnal Inovasi Pendidikan dan Sains
This study explores the implementation and actualization of human resource development (HRD) programs aimed at enhancing teacher professionalism in junior high schools within Batam’s hinterland.
Pusvariauwaty Pusvariauwaty, Tubagus Pamungkas, Alpino Susanto   +2 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Clinical confidence following an interprofessional educational program on eating disorders for health care professionals: a qualitative analysis

Journal of Multidisciplinary Healthcare, 2012
Gunn Pettersen,1 Jan H Rosenvinge,1 Kari-Brith Thune-Larsen,2 Rolf Wynn1,31Faculty of Health Sciences, University of Tromsø, Tromsø, Norway; 2Oslo University Hospital, Oslo, Norway; 3Division of Addictions and Specialized Services ...
Pettersen G, Rosenvinge JH, Thune-Larsen KB, Wynn R   +3 more
doaj  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Development of an Interactive E-book based on the ARCS Model to Improve Students' Arabic Writing Skills

Jurnal Al Bayan: Jurnal Jurusan Pendidikan Bahasa Arab
Arabic writing skill is the most difficult skill where many students are weak in this skill and the available teaching materials are less engaging. Therefore development of teaching materials based on the ARCS model was needed to help improve students ...
Indaha Nur Wahyuni, Sariyatun Sariyatun, Moh. Muchtarom, Hanan Alhakimi   +3 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Principal's Leadership as An Educational Supervisor In Improving The Quality of Teaching and Learning

Jurnal Inovasi Pendidikan dan Sains
This study aims to analyze the strategic role of the principal as an educational supervisor in improving the sustainable quality of teaching and learning at Tabgha Mulia School, Batam.
Ratna Sagala, Tubagus Pamungkas, Ramdhani Ramdhani   +2 more
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Assessing academic anxiety in d/Deaf, DeafBlind, and hard of hearing individuals

Frontiers in Psychology
Students encounter many challenges to academic success. Whereas some students thrive in stressful environments, other students falter. Some students also encounter social and emotional factors that might detract from academic achievement, including ...
Rachel Gabriella Pizzie, Christina Eun-Young Kim, Rachel Marie Sortino, Rachel Inghram   +3 more
doaj   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source