Results 71 to 80 of about 2,940,980 (314)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Innovation Model of Digital Library Management to Enhance Literacy Culture in Senior High Schools

Jurnal Inovasi Pendidikan dan Sains
This study aims to analyze how digital library innovations cultivate a reading culture in senior high schools. The specific objectives are to examine the planning, implementation, evaluation, and management models applied in school-based digital library ...
Noviyanti Noviyanti, Siraj Siraj, Cut Khairani   +2 more
doaj   +1 more source

Ada education in a software life-cycle context [PDF]

Some of the experience gained from a comprehensive educational program undertaken at The Charles Stark Draper Lab. to introduce the Ada language and to transition modern software engineering technology into the development of Ada and non-Ada applications
Clough, Anne J.
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Mapping Teacher’s Readiness to Improve the Government Policy in Implementing Higher-Order Thinking Skills-Based Learning

Qubahan Academic Journal
Recently, there have been many trainings aimed at investigating pedagogical practices among teachers related to HOTS-based teaching in the context of Indonesian education.
Taufiq Lilo Adi Sucipto , Sajidan Sajidan, Muhammad Akhyar, Roemintoyo Roemintoyo   +3 more
doaj   +1 more source

Supporting Success: Why and How to Improve Quality in After-School Programs [PDF]

, 2008
This report examines the program improvement strategies, step-by-step, that allowed The James Irvine Foundation's CORAL initiative to achieve the levels of quality needed to boost the academic success of participating students.
Jessica Sheldon, Leigh Hopkins
core  

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Linking Instructional Supervision to Teacher Development and School Growth in Early-Stage Islamic Elementary Institutions

Jurnal Inovasi Pendidikan dan Sains
Academic supervision is crucial for shaping teacher quality in educational institutions, yet its implementation in newly established Islamic schools remains underexplored.
Sahbana Ridha, Aslamiah Aslamiah, Noorhapizah Noorhapizah, Novitawati Novitawati   +3 more
doaj   +1 more source

International Partnerships: A Model for Educational Organizations [PDF]

, 2018
Opportunities exist for faculty and students within educational leadership preparation programs to participate in international initiatives within developing countries.
Achtem, Janice M., Hickey, Wesley D., Nuner, Joyce   +2 more
core   +1 more source