Results 81 to 90 of about 2,940,980 (314)

Assessments as Teaching and Research Tools in an Environmental Problem-Solving Program for In-Service Teachers [PDF]

open access: yes, 2002
This article discusses the use of a scenario-based assessment tool in two environmental geoscience in-service programs for middle school and high school teachers.
Barbara Cooper   +2 more
core   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

Postponing Sexual Involvement Parent/Guardian Survey 2002 [PDF]

open access: yes, 2002
The Postponing Sexual Involvement Program is an educational curriculum designed to help teenagers learn to cope with and resist social and peer pressures to become sexually active at inappropriately early ...

core  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Clinical confidence following an interprofessional educational program on eating disorders for health care professionals: a qualitative analysis

open access: yesJournal of Multidisciplinary Healthcare, 2012
Gunn Pettersen,1 Jan H Rosenvinge,1 Kari-Brith Thune-Larsen,2 Rolf Wynn1,31Faculty of Health Sciences, University of Tromsø, Tromsø, Norway; 2Oslo University Hospital, Oslo, Norway; 3Division of Addictions and Specialized Services ...
Pettersen G   +3 more
doaj  

THE DEVELOPMENT OF CAI BASED ANDROID IN SOLAR SYSTEM AND UNIVERSE TOPIC FOR TENTH-GRADE

open access: yesGeosfera Indonesia, 2019
The aim of the research to generate learning media, thus the media development will assist students to understand the content during the learning process. Besides establishing a product, the manual guide was also arranged.
M Marwiyah, R Rusijono, Fajar Arianto
doaj   +1 more source

How accurately do instructors judge students’ attitudes online? A measurement of expectations and level of satisfaction with an Online Information Systems masters program [PDF]

open access: yes, 2002
In order to run a successful educational program, instructors as well as staff members must constantly review and adapt to the expectations, concerns, demographics and satisfaction level of their student consumers.
Macht, Lauren‐Nicole, Preece, Jenny
core   +2 more sources

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

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