Results 61 to 70 of about 156,404 (243)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Problems of providing safe meals for students in educational institutions

RUDN Journal of Ecology and Life Safety, 2012
Main problems of organizing safe meal provision system in educational institutions are analyzed in the article. It is shown that safe nutrition not only determines quality of life, but also plays a major role in disease prevention and maintaining health ...
O V Potkina, S V Goryunova
doaj  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Exploring the experiences and outcomes of children and young people receiving support for special educational needs over time in England: a qualitative study

Frontiers in Education
BackgroundOne in five school-aged children and young people (CYP) in England are identified as having a special educational need or disability (SEND) requiring additional support.
Jennifer Saxton, Jacob Matthews, Isaac Winterburn, Helen Casey, Ania Zylbersztejn, Sarah Barnes, Poppy Hall, Charlotte Tripp, Kristine Black-Hawkins, Tamsin Ford   +9 more
doaj   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Life, learning and flexible delivery

Journal of Open, Flexible and Distance Learning, 2012
This paper explores the thesis that flexible learning is a critical development in assuring high quality educational provision for individuals at all stages of their lives, but that there are dangers it will be compromised by the actions of education ...
Bruce King
doaj   +2 more sources

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Provision of feedback to medical teachers on their educational performance: perspectives of internal medicine teachers

Advances in Medical Education and Practice, 2019
Sepideh Jamshidian,1 Fariba Haghani,1 Nikoo Yamani,1 Mohammad Reza Sabri2 1Department of Medical Education, Medical Education Research Center, Isfahan University of Medical Sciences, Isfahan, Iran; 2Department of Pediatrics, Pediatric Cardiovascular ...
Jamshidian S, Haghani F, Yamani N, Sabri MR   +3 more
doaj  

UK Built Environment postgraduate programme provision: sectoral context, viability and educational implications

Cogent Education
Postgraduate (PG) Built Environment education provides higher level skills, yet, concerns of losing such provision exist, as UK universities are experiencing financial challenges from systemic governmental underfunding.
Alan M. Forster, Laurent Galbrun, Nick Pilcher, Stuart Tennant, Nigel Craig, Mike Murray   +5 more
doaj   +1 more source

Sociological monitoring of customer satisfaction with the quality of the educational services

Высшее образование в России, 2022
The article focuses on the properties and characteristics of the educational process, which determine its ability to respond to the educational needs of specific customers.
G. . Gaidukova
doaj