Results 81 to 90 of about 419,652 (290)

What a difference a term makes:the effect of educational attainment on marital outcomes in the UK [PDF]

open access: yes, 2013
In the past, students in England and Wales born within the first 5 monthsof the academic year could leave school one term earlier than those born later inthe year.
D Lee   +24 more
core   +3 more sources

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

A Simple Model of Educational Production [PDF]

open access: yes
There is a large body of literature on the effect of educational resources on student performance, such as teacher qualification, class size, and physical resources in school.
Jaag, Christian
core   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Рабочая учебная программа дисциплины Спортивные игры и методика их преподавания [PDF]

open access: yes, 2015
Програма визначає обсяги знань, які повинен опанувати бакалавр відповідно до вимог освітньо-кваліфікаційної характеристики, алгоритму вивчення навчального матеріалу дисципліниThe program determines the volume of knowledge that should master the bachelor ...
Косік, Микола Сергійович
core  

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

State of Professional Preparation of Future Physical Training Teachers to Teach Swimming at Children’s Holiday Camps

open access: yesPhysical Education Theory and Methodology, 2016
The paper reviews the state of professional preparation of future physical education teachers relying on the comparison of the fundamental documents that shape the professional competence of a swimming instrucror at children’s holiday camps.
C. М. Клімакова
doaj   +1 more source

Success Despite Starting out at a Disadvantage: What Helps Second-Generation Migrants in France and Germany? [PDF]

open access: yes
The educational and employment trajectories of migrant children in France and Germany are extremely diverse. The few successful ones dominate the public eye.
Ariane Jossin   +3 more
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

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