Results 41 to 50 of about 3,258,851 (300)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Quality Education

, 2016
This paper addresses the issue of quality education: the importance, the levels of training, the lifelong training, customer requirements, customer satisfaction, social and economic development. Based on the literature the study will demonstrate how quality is primarily a problem of education, of culture, of the present and of the future. We are moving
Paraschivescu, A., Paraskivesku, A., Şavga, L.A.   +2 more
openaire   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The self-attitude of parents raising children with special needs

Экспериментальная психология
Context and relevance. We studied the peculiarities of the self-attitude of fathers and mothers of one or more children with special needs. All the participants are Russian-speaking men and women, residents of Russia. Objective.
Y.V. Borisenko, A.A. Semenichheva
doaj   +1 more source

Quality management in schools: Analysis of mediating factors

South African Journal of Education, 2018
The objective of this study is to contribute to Quality Management Systems (QMS) and their impact on schools in the Basque Country, Spain. Specifically, it analyses two models: the EFQM Excellence Model, which originated in the business world, and the ...
Fernando Díez, Ioseba Iraurgi, Aurelio Villa   +2 more
doaj   +1 more source

The quality of measures of educational performance: an empirical approach [PDF]

, 2013
We assess whether the difference between teacher and test-based assessment at age 14 and 10 -as a measure of bias or uncertainty in assessment specifically– is linked systematically to observable pupil characteristics.
Marcenaro-Gutiérrez, Óscar David
core  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Research quality assessment in education: impossible science, possible art? A response to David Bridges [PDF]

, 2009
Response to keynote presentation by Prof David Bridges on the topic of quality in the Research Assessment Exercise.
Devecchi, Cristina
core