Results 61 to 70 of about 3,258,851 (300)

Administrative decentralization policies and developments in educational quality management in Peru

open access: yesFrontiers in Education
The objective of the research was to determine the relationship between decentralized policies, techniques, and human resources directly related to improving educational quality and the influence of supervisory actions and information and communication ...
Dora Amalia Mayta Huiza   +4 more
doaj   +1 more source

Performance of Missing Data Approaches Under Nonignorable Missing Data Conditions

open access: yesMethodology, 2020
Approaches for dealing with item omission include incorrect scoring, ignoring missing values, and approaches for nonignorable missing values and have only been evaluated for certain forms of nonignorability.
Steffi Pohl, Benjamin Becker
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Education and life satisfaction: perception or reality? [PDF]

open access: yes
Using data from the Gallup World Poll, this paper analyze the way in which perceptions on thequality of education affect wellbeing. In addition, we explore if educational quality perceptions aredetermined by objective educational outputs, such as ...
Carolina Mejía   +2 more
core  

Good practices, innovation or scientific research in education? A conceptual reflection [PDF]

open access: yes, 2020
In this work a conceptual delimitation of "good teaching practices", "educational innovation" and "educational research" is proposed, based on both the experimental design and the quality of the evidence provided by these ...
Hernández Fernández, Antonio
core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

School Quality, Educational Attainment and Aggregation Bias [PDF]

open access: yes
Data from 31 countries participating in the Programme for International Student Assessment (PISA) is used to estimate education production functions for reading literacy.The analysis suggests that the probability of finding statistically significant and ...
Michael Fertig, Robert E. Wright
core  

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