Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
, 2003 The purpose of this activity is to build an instrument that can be used to measure water temperature. Students construct a soda-bottle thermometer, which is similar to the thermometer used by GLOBE schools.
The GLOBE Program, UCAR (University Corporation for Atmospheric Research)
core
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Virtual Human–Delivered Interviews for Patients With Chronic Pain: Feasibility, Acceptability, and a Pilot Randomized Trial of Standard Medical, Psychosocial, and Educational Interviews [PDF]
, 2023 Doerte U. Junghaenel +7 more
openalex +1 more source
Virtual reality learning resources in building pathology [PDF]
, 2006 Building surveying students must be capable of analysing the condition of buildings and their components and, where this falls below an agreed standard, make recommendations for their repair.
Dickinson, I +4 more
core
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Architectonics of Pedagogical Practice Programs for Master’s Degree Students of Pedagogical Specialities under Introduction of New Federal State Educational Standards [PDF]
, 2020 Tat'yana Aleksandrovna Baklashova +2 more
openalex +1 more source
Non-Standard Words as Features for Text Categorization
, 2014 This paper presents categorization of Croatian texts using Non-Standard Words (NSW) as features. Non-Standard Words are: numbers, dates, acronyms, abbreviations, currency, etc.
Beliga, Slobodan +1 more
core +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Organizing Educational Activity of 5th-Grade Pupils with Hearing Impairment under the Conditions of Introducing the Federal State Educational Standard of Primary General Education for Pupils with Disabilities [PDF]
, 2020 Ol'ga Demidovna Timofeeva +1 more
openalex +1 more source