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The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Why Do We Need Humanities? [PDF]
The article is a philosophical reflection of the current status of the humanities in Slovakia. In many areas of our society there is an evident deficit in humanities-science knowledge, reflected also in parliamentary election results in 2016 and having ...
Švihura, Lukáš
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LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
The Role of Child Health and Economic Status in Educational, Health and Labour Market Outcomes in Young Adulthood [PDF]
The Ontario Child Health Study provides the first opportunity in Canada to assess directly the relationship between socio-economic and health status in childhood and levels of completed schooling, health status and labour market success in young ...
Martin Dooley, Paul Contoyannis
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Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Role of Socioeconomic Status (SES) in Globe Injuries: A Review
Panagiotis Kousiouris,1,* Olga Klavdianou,1,* Konstantinos AA Douglas,1 Nikolaos Gouliopoulos,2 Klio Chatzistefanou,1 Maria Kantzanou,3 Georgios S Dimtsas,1 Marilita M Moschos1 1 1st Department of Ophthalmology, National and Kapodistrian ...
Kousiouris P +7 more
doaj
Family Unity, Family Health: How Family-Focused Immigration Reform Will Mean Better Health for Children and Families [PDF]
This report builds on a body of evidence on the impact of immigration policy on communities, paying particular attention to the health and mental health of children and families.Using existing research, predictive quantitative analysis and data from a ...
Alice Hu +3 more
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We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
The Importance of Patient Education: the Attitude of Nurses in the Hospitals of Babol
BACKGROUND AND OBJECTIVE: Patient education is one of the quality standards of nursing care and affects on the costs, recovery and cure rate of the patients.
Maryam Farouki Far +3 more
doaj

