Results 121 to 130 of about 812,919 (311)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Relação entre cárie, gengivite e fluorose e nível socioeconômico em escolares

open access: yesRevista de Saúde Pública
OBJETIVO: Determinar a relação entre o nível socioeconômico e a prevalência de cárie dentária, gengivite e fluorose em escolares brasileiros. MÉTODOS: Foram examinados mil escolares de 12 anos de idade provenientes das redes particular e pública de ...
Marisa Maltz, Berenice Barbachan e Silva
doaj  

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Girls' career aspirations : the impact of parents' economic and educational status on educational and career pathways

open access: yes, 2015
This research investigates relationships between parental socio economic status and daughters' career aspirations; linking family background and the career choices made by teenage girls.
Pfingst, Catherine J.
core  

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

Which background factors matter more in intergenerational educational attainment: Social class, cultural capital or cognitive ability? A random effects approach [PDF]

open access: yes
The sociological research literature on intergenerational educational attainment has highlighted three types of theoretical frameworks in explaining to what extent social origins influences people’s educational choices and possibilities.
Anders Holm, Mads Meier Jæger
core  

Association Between Educational Status and Mortality According to Diabetes Status Among US Adults. [PDF]

open access: yesMayo Clin Proc Innov Qual Outcomes, 2023
Komura T, Kondo N, Bhatt K, Inoue K.
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Gender differences in social mortality differentials in Switzerland (1990-2005) [PDF]

open access: yes
Using data from the 1990 and 2000 Swiss Federal Censuses linked to the death records of the years 1990-1995 and 2000-2005, this paper investigates gender differences in mortality differentials by level of educational achievement and by marital status. In
Reto Schumacher, Sarah Vilpert
core  

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