Results 101 to 110 of about 812,919 (311)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Keterkaitan Latar Belakang Pendidikan, Pengetahuan Ekosistem Mangrove, Status Ekonomi Keluarga dan Sikap dengan Perilaku Nelayan dalam Pelestarian Hutan Mangrove

, 2014
: Many areas of the Mangrove is  in Indonesia were damaged. The Many factor caused the mangrove damage, are like social economic conditions of fisherman at around the mangrove.
Syaban, Rahmat Ali
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

On the relationship between socio-economic status and educational and career aspirations in the middle years of schooling

, 2014
Strategies designed to increase the participation of youth from traditionally underrepresented backgrounds in higher education in Australia have had little impact.
Holmes, Kathryn (R18458), Albright, Jim, Gore, Jennifer, Ellis, Hywel, Berger, Nathan (R18455), Smith, Max, Southgate, Erica   +6 more
core  

Perspectiva masculina acerca do aborto provocado

Revista de Saúde Pública
OBJETIVO: Analisar a perspectiva de homens de uma comunidade universitária que viviam em união legal ou consensual acerca do aborto provocado. MÉTODOS: Estudo descritivo de corte transversal em que se analisaram informações de 361 entrevistados ...
Graciana Alves Duarte, Augusta Thereza de Alvarenga, Maria José M Duarte Osis, Aníbal Faúndes, Ellen Hardy   +4 more
doaj  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Strength, Sources, and Temporal Development of Primary Effects of Families´ Social Status on Secondary School Choice [PDF]

We analyze the relative importance of primary and secondary effects of both parents’ educational and occupational status on whether an upper or a less ambitious secondary school track is chosen after primary school in Germany.
Stocké, Volker
core  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Exploring educational mobility in Europe [PDF]

This paper is concerned with the investigation of the intergenerational mobility of education in several European countries and its changes across birth cohorts (1940-1980) using a new mobility index that considers the total degree of mobility as the ...
Jorge Calero, José Luís Raymond, Antonio Di Paolo   +2 more
core  

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source