Results 91 to 100 of about 531,326 (318)

Mathematics education as a systems of society

open access: yesRevista de Educação Matemática, 2023
Este ensaio explora a filosofia da educação matemática a partir de uma perspectiva sociológica histórica. Este examina a natureza da construção de significado à medida que os sistemas sociais de matemática e educação matemática emergem como parte da sociedade.
openaire   +2 more sources

Requirements for educational support tools in Virtual Worlds

open access: yes, 2012
Paper number 65Virtual Worlds have been used for online gaming, socialising, business advertising and education. As the educational uses become more sophisticated from early information advertising and teaching resources to simulated laboratory and ...
Duncan, Ishbel Mary Macdonald   +1 more
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Educational Implications of School Systems at Different Stages of Schooling [PDF]

open access: yes
In educating students national public school systems use different methods of grouping students by ability across schools. We consider four different school systems of student allocation at different stages of schooling and their educational implications.
Kang Changhui, Jung Hur
core  

DIALOGUE AS NECESSITY OF PRESENT- DAY EDUCATIONAL PROCESS

open access: yes, 2014
Thearticle is devoted to learning problems in contemporary school, which havetheir roots in present- day information society. The pupils are more self-informed through different IT channels.
Purēns, Vilnis; Riga Teacher Training and Educational Management Academy
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Initiating a new information systems course: a case study in educational innovation

open access: yes, 2008
DigitalCommons@Kennesaw State University © 2008If South Africa is to transform its educational landscape, access to higher education is crucial. However, if equity of access is not coupled with equity of success, participation, and relevance, access can ...
Johnston, Kevin   +2 more
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Systematic development of courseware systems [PDF]

open access: yes, 2005
Various difficulties have been reported in relation to the development of courseware systems. A central problem is to address the needs of not only the learner, but also instructor, developer, and other stakeholders, and to integrate these different ...
Pahl, Claus
core  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

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