Results 31 to 40 of about 512,122 (313)
Educate for Technological Innovation [PDF]
Proceedings of the Design Society: International Conference on Engineering Design, 2019 AbstractAt Polytechnics design & engineering students are taught about state-of-the-art technical knowledge. Students become qualified engineers and learn to innovate artifacts related to their domain.Not taught is how to develop new engineering knowledge within a multidisciplinary context of stakeholders, companies and regulations.
Smulders, F.E.H.M. (author) +4 more
openaire +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Educational technology and education in technology
Australasian Journal of Educational Technology, 1987 <span>This paper discusses the impact of new technology on education. It is concerned with new technology as a method of delivery, a subject and an object of education. Nigel Paine argues that, if the educational world does not respond to the new networks being established and the new curriculum areas being developed, then alternative means of ...
openaire +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The Emergence of Educational Technology [PDF]
, 2008 This paper traces the emergence of Information Technology (IT) for educational purposes. It begins with a discourse on the relationship between culture and educational technology. A key premise is that culture is an important influence in education. Similarly, the evolution of educational technology is very much intertwined with culture.
Elizabeth Koh 0001, John Lim
openaire +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The Role of Technology in Redesigning the Modern Education System
Jurnal Teknologi PendidikanTechnological advancements have played a vital role in redesigning the modern education system to be more adaptive, effective, and inclusive. However, despite rapid development, many educational institutions are still struggling to align with 21st ...
Suhada Suhada +2 more
doaj +1 more source
The Educational Technology is Technology Education Manifesto
Journal of Technology Education, 2003 Published ...
openaire +2 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source