Results 71 to 80 of about 512,122 (313)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Implementing Cost-Effective Educational Technology: Some Reflections

, 1977
Blaschke begins by writing that the radical technology change and improvement in education to make educational technology more cost-effective had not been completed.
Sweeney, John, Blaschke, Charles
core  

Research Trends and Issues in Educational Technology: a Content Analysis of Tojet (2008-2011) [PDF]

, 2012
WOS: 000308976800028This study has been conducted to evaluate the contents of articles published in the Turkish Online Journal of Educational Technology (TOJET) between 2008 and 2011.
Bozkaya, Müjgan, Kumtepe, Evrim Genç, Aydın, İrem Erdem   +2 more
core  

Psicologia da educação e as tecnologias digitais de informação e comunicação

Psicologia Escolar e Educacional
O objetivo deste estudo é discutir repercussões das Tecnologias Digitais de Informação e Comunicação (TDICs) no campo da Psicologia da Educação. O estudo é teórico e está amparado numa revisão narrativa da literatura científica que analisou diferentes ...
Fabio Scorsolini-Comin
doaj   +1 more source

Educational Technology: The Influence of Theory

Journal of Interactive Media in Education, 2002
: In this paper we explore the role of theories in current practice in educational technology. We review a range of writings from the past 30 years on the nature of learning technology research.
Kim Issroff, Eileen Scanlon
doaj   +1 more source

COVID-19 Epidemic as E-Learning Boost? Chronological Development and Effects at an Austrian University against the Background of the Concept of “E-Learning Readiness”

Future Internet, 2020
The COVID-19 crisis influenced universities worldwide in early 2020. In Austria, all universities were closed in March 2020 as a preventive measure, and meetings with over 100 people were banned and a curfew was imposed.
Martin Ebner, Sandra Schön, Clarissa Braun, Markus Ebner, Ypatios Grigoriadis, Maria Haas, Philipp Leitner, Behnam Taraghi   +7 more
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Evaluation of education

, 1973
Comprend des ...
Educational Technology
core  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source