Results 41 to 50 of about 151,290 (231)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
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Fracture and Structural Integrity, 2019 The objective of the study is to introduce an experimental uncertainty budget process for concrete compressive strength test, based on a protocol that incorporates effects of multiple factors significant for the measurement result.
Stamatia Gavela +4 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
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Journal of Curriculum Studies, 2019 本書對於全球化過程中教育改革和政策的借用相關議題提供一個基礎的認識。全球化對於教育政策有深遠的影響，尤其是對發展中國家之教育。全球化的影響已不僅止於政治層面，甚至已深入到生活層面。猶記筆者公費留學剛到美國唸書時，就已選修著名教授M. Peters和F. Rizvi合開的全球化課程，當時兩位教授於課堂上常會彼此互動論辯，激盪出許多火花，也讓學生對於全球化有更多層面的觀點與思維。課堂中的學生來自世界各地，全球化議題的討論更顯得如此貼近實際生活，課堂之餘，學生的交流也確實感受到全球化和在地化並存融合的氛圍 ...
劉子彰 Tze-Changm Liu
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Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
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Convergence and Divergence of the Solutions of a Neutral Difference Equation
Journal of Applied Mathematics, 2011 We investigate the asymptotic behavior of the solutions of a neutral type difference equation of the form Δ[𝑥(𝑛)+𝑐𝑥(𝜏(𝑛))]+𝑝(𝑛)𝑥(𝜎(𝑛))=0, where 𝜏(𝑛) is a general retarded argument, 𝜎(𝑛) is a general deviated argument (retarded or advanced), 𝑐∈ℝ, (𝑝(𝑛))𝑛 ...
G. E. Chatzarakis, G. N. Miliaras
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Oscillations of advanced difference equations with variable arguments
Electronic Journal of Qualitative Theory of Differential Equations, 2012 Consider the first-order advanced difference equation of the form \begin{equation*} \nabla x(n)-p(n)x(\mu (n))=0\text{, }\ n\geq 1\, [\Delta x(n)-p(n)x(\nu (n))=0, n\geq 0], \end{equation*} where $\nabla $ denotes the backward difference operator ...
George Chatzarakis, Ioannis Stavroulakis
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
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MathematicsTo understand phase-transition processes like solidification, phase-field models are frequently employed. In this paper, we study a finite-difference Crank–Nicolson–ADI scheme for a class of nonlinear parabolic isotropic systems.
Chrysovalantis A. Sfyrakis +1 more
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