Results 61 to 70 of about 518,624 (266)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Convergence and Divergence of the Solutions of a Neutral Difference Equation
Journal of Applied Mathematics, 2011 We investigate the asymptotic behavior of the solutions of a neutral type difference equation of the form Δ[𝑥(𝑛)+𝑐𝑥(𝜏(𝑛))]+𝑝(𝑛)𝑥(𝜎(𝑛))=0, where 𝜏(𝑛) is a general retarded argument, 𝜎(𝑛) is a general deviated argument (retarded or advanced), 𝑐∈ℝ, (𝑝(𝑛))𝑛 ...
G. E. Chatzarakis, G. N. Miliaras
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Diversitas JournalWe are pleased to introduce the Special Issue on Sustainability in Asia-Pacific: Multidisciplinary Insights and Innovations, a collaboration between Diversitas Journal, the Asia-Pacific Consortium of Research and Educators, Inc.
Racidon Bernarte
doaj +1 more source
RECEPTIVE STRATEGIES OF Y. KLAVDIEV'S PLAY "THE YAKUZA DOGS"
Вестник Кемеровского государственного университета, 2017 The article discusses the play by contemporary playwright Yuri Klavdiev "TheYakuza Dogs." Here is a detailed (but not exhaustive) analysis of the cultural codes.
T. N. Volkova
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Guiding principles: Oregon Educators Benefit Board
, 2007 This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF caption (viewed on Sept.
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
MathematicsTo understand phase-transition processes like solidification, phase-field models are frequently employed. In this paper, we study a finite-difference Crank–Nicolson–ADI scheme for a class of nonlinear parabolic isotropic systems.
Chrysovalantis A. Sfyrakis +1 more
doaj +1 more source