Results 21 to 30 of about 69,972 (303)

Case study of patient affected by the mosaic form of de-novo p63 related EEC syndrome

, 2023
reservedThe Ectrodactyly-Ectodermal dysplasia-Clefting (EEC) syndrome is a rare genetic disorder that is inherited in an autosomal dominant manner, resulting in ocular morbidity, hand and foot malformations.
ANARI BEIGDILOO, HANIEH
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A COMPARATIVE ANALYSIS OF EUROPEAN EDUCATIONAL PROGRAMS IN THE LATE 80’S AND EARLY 90’S: COMETT, ERASMUS, PETRA, LINGUA, TEMPUS, AND EUROTECNET [PDF]

Annals of the "Ovidius" University of Constanţa. Political Science Series
This study delves into the impact of key European educational programs launched between the late 1980s and early 1990s, namely COMETT, Erasmus, PETRA, Lingua, TEMPUS, and Eurotecnet.
Costel COROBAN, Cristina-Iulia MARINESCU (GÎLĂ)   +1 more
doaj   +1 more source

Gene therapy approaches for correction of EEC phenotype in the cornea

, 2023
reservedEctrodactyly–ectodermal dysplasia–clefting syndrome (EEC) syndrome is an autosomal dominant disease caused by mutations in the TP63 gene. p63 is a transcription factor essential for ectodermal development, oocytes genetic quality control and ...
FREGONESE, SILVIA
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Integrated microRNA and mRNA transcriptome sequencing reveals the potential roles of miRNAs in stage I endometrioid endometrial carcinoma. [PDF]

PLoS ONE, 2014
Endometrioid endometrial carcinoma (EEC) is the most dominant subtype of endometrial cancer. Aberrant transcriptional regulation has been implicated in EEC.
Hanzhen Xiong, Qiulian Li, Shaoyan Liu, Fang Wang, Zhongtang Xiong, Juan Chen, Hui Chen, Yuexin Yang, Xuexian Tan, Qiuping Luo, Juan Peng, Guohong Xiao, Qingping Jiang   +12 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source

Comparative characteristics of the transcriptional activity of CDH1, CTNNB1, VEGFA genes and expression of proteins E-cadherin, β-catenin and VEGFA, coded by these genes in metastatic and non-metastatic endometrioid endometrial carcinoma

Patologìâ, 2016
The violation of Wnt-signaling pathway and cyclic neoangiogenesis is early events in endometrial carcinogenesis. In this process an important role is played by epigenetic modifications and mutations of CDH1, CTNNB1, VEGFA genes, followed by expression ...
V. A. Tumanskiy, A. V. Chepets, А. М. Kamyshnyi   +2 more
doaj   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Single-cell transcriptomic analysis highlights origin and pathological process of human endometrioid endometrial carcinoma

Nature Communications, 2022
Many aspects of the tumourigenesis of endometrioid endometrial cancers (EEC) are still poorly understood. Here, the authors use single-cell transcriptomics to characterise EEC tumours and their microenvironment across different stages, and reveal ...
Xiaojun Ren, Jianqing Liang, Yiming Zhang, Ning Jiang, Yuhui Xu, Mengdi Qiu, Yiqin Wang, Bing Zhao, Xiaojun Chen   +8 more
doaj   +1 more source

Development of an advanced therapy medicinal product for the treatment of limbal stem cell deficiency in EEC patients

, 2022
reservedLa sindrome EEC è causata da mutazioni puntiformi in eterozigosi che colpiscono il dominio di legame al DNA del fattore di trascrizione p63.
PIAIA, MORENO
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