Results 41 to 50 of about 69,972 (303)

Tau expression and phosphorylation in enteroendocrine cells

Frontiers in Neuroscience, 2023
Background and objectiveThere is mounting evidence to suggest that the gut-brain axis is involved in the development of Parkinson’s disease (PD). In this regard, the enteroendocrine cells (EEC), which faces the gut lumen and are connected with both ...
Guillaume Chapelet, Nora Béguin, Blandine Castellano, Isabelle Grit, Pierre de Coppet, Thibauld Oullier, Michel Neunlist, Hervé Blottière, Malvyne Rolli-Derkinderen, Gwenola Le Dréan, Pascal Derkinderen   +10 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Wideband 0.5–50 GHz double‐ridged guide horn antenna using coaxial‐to‐ridge waveguide launcher

IET Microwaves, Antennas & Propagation
Ever‐increasing bandwidth requirements from various industries drive the need for the ever‐increasing bandwidth of antennas used for testing.
Bennie Jacobs, Johann W. Odendaal, Johan Joubert   +2 more
doaj   +1 more source

Identification of novel Lynch syndrome mutations in Chinese patients with endometriod endometrial cancer

Cancer Biology & Medicine, 2020
Objective: Lynch syndrome (LS) predisposes patients to early onset endometrioid endometrial cancer (EEC). However, little is known about LS-related EEC in the Chinese population.
Caixia Ren, Yan Liu, Yuxiang Wang, Yan Tang, Yawei Wei, Congrong Liu, Hongquan Zhang   +6 more
doaj   +1 more source

“New vs. old Europe”: Contested hegemonies and the dual-guarantee strategy of the East European countries [PDF]

Međunarodni Problemi, 2005
The paper analyses the East European countries' (EEC) security strategy in light of contesting US and Franco-German hegemonic projects. The EEC' s quest for a dual-guarantee strategy, which aims to get hard security from the US through NATO and soft ...
Türkes Mustafa
doaj   +1 more source

Clinical features related to lymphatic metastasis in grade 3 endometroid endometrial cancer: a retrospective cross-sectional study

Chinese Medical Journal, 2021
. Background. Endometrial cancer (EC) has been one of the most general cancers with respect to gynecological malignancies; however, there are debates on clinical strategies concerning treatments especially for patients with grade 3 (G3) endometroid ...
Bo Wang, Qian Wang, Yue Shi, Wen-Yu Shao, Jiong-Bo Liao, Xue-Zhen Luo, Xiao-Jun Chen, Chao Wang, Ning-Ning Wang   +8 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The EEC-Mexican Agreement: Time for Reevaluation? [PDF]

, 1988
This Note argues that the EEC and Mexico should modify their current agreement. Part I examines the terms of the EEC-Mexican Agreement. Part II discusses the changing economic factors in the EEC and Mexico that dictate the need for a new agreement ...
Woods, Therese M.
core   +1 more source