Results 51 to 60 of about 69,972 (303)

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

ความร่วมมือในโซ่อุปทานในอุตสาหกรรมเขตพัฒนาพิเศษภาคตะวันออก (EEC) ของประเทศไทย [PDF]

open access: yes
In today’s era of intense business competition and rapidly changing environments, supply chain collaboration has become a critical strategy for enhancing competitiveness and increasing operational flexibility.
Ruamchart, Baweena
core   +1 more source

EEC Elections [PDF]

open access: yes, 1978
Notice of a General Members meeting to discuss the EEC ...
Sinn Fein
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Aligned Space Time Block Codes for the 2-User X Channel with Secrecy Constraints

open access: yesInternational Journal of Antennas and Propagation, 2015
Interference alignment (IA) is a technique used to reduce the dimension of the interference, where consequently the multiplexing rate is increased. In the 2-user X channel, combining IA with space-time block codes increases the diversity gain.
Manar Mohaisen
doaj   +1 more source

Diagnóstico prenatal del Síndrome EEC [PDF]

open access: yes, 2001
Se presenta un caso de diagnóstico prenatal ecográfico del Síndrome EEC (Ectrodactilia, Displasia Ectodérmica y Labio y Paladar Hendidos), en una familia con tres generaciones de ...
Mantilla, J.   +9 more
core  

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