Results 31 to 40 of about 60,910 (307)

Enteroendocrine Progenitor Cell–Enriched miR-7 Regulates Intestinal Epithelial Proliferation in an Xiap-Dependent MannerSummary

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2020
Background & Aims: The enteroendocrine cell (EEC) lineage is important for intestinal homeostasis. It was recently shown that EEC progenitors contribute to intestinal epithelial growth and renewal, but the underlying mechanisms remain poorly understood ...
Ajeet P. Singh   +20 more
doaj   +1 more source

Integrated microRNA and mRNA transcriptome sequencing reveals the potential roles of miRNAs in stage I endometrioid endometrial carcinoma. [PDF]

open access: yesPLoS ONE, 2014
Endometrioid endometrial carcinoma (EEC) is the most dominant subtype of endometrial cancer. Aberrant transcriptional regulation has been implicated in EEC.
Hanzhen Xiong   +12 more
doaj   +1 more source

A COMPARATIVE ANALYSIS OF EUROPEAN EDUCATIONAL PROGRAMS IN THE LATE 80’S AND EARLY 90’S: COMETT, ERASMUS, PETRA, LINGUA, TEMPUS, AND EUROTECNET [PDF]

open access: yesAnnals of the "Ovidius" University of Constanţa. Political Science Series
This study delves into the impact of key European educational programs launched between the late 1980s and early 1990s, namely COMETT, Erasmus, PETRA, Lingua, TEMPUS, and Eurotecnet.
Costel COROBAN   +1 more
doaj   +1 more source

Gene therapy approaches for correction of EEC phenotype in the cornea

open access: yes, 2023
reservedEctrodactyly–ectodermal dysplasia–clefting syndrome (EEC) syndrome is an autosomal dominant disease caused by mutations in the TP63 gene. p63 is a transcription factor essential for ectodermal development, oocytes genetic quality control and ...
FREGONESE, SILVIA
core  

Single-cell transcriptomic analysis highlights origin and pathological process of human endometrioid endometrial carcinoma

open access: yesNature Communications, 2022
Many aspects of the tumourigenesis of endometrioid endometrial cancers (EEC) are still poorly understood. Here, the authors use single-cell transcriptomics to characterise EEC tumours and their microenvironment across different stages, and reveal ...
Xiaojun Ren   +8 more
doaj   +1 more source

Case study of patient affected by the mosaic form of de-novo p63 related EEC syndrome

open access: yes, 2023
reservedThe Ectrodactyly-Ectodermal dysplasia-Clefting (EEC) syndrome is a rare genetic disorder that is inherited in an autosomal dominant manner, resulting in ocular morbidity, hand and foot malformations.
ANARI BEIGDILOO, HANIEH
core  

Comparative characteristics of the transcriptional activity of CDH1, CTNNB1, VEGFA genes and expression of proteins E-cadherin, β-catenin and VEGFA, coded by these genes in metastatic and non-metastatic endometrioid endometrial carcinoma

open access: yesPatologìâ, 2016
The violation of Wnt-signaling pathway and cyclic neoangiogenesis is early events in endometrial carcinogenesis. In this process an important role is played by epigenetic modifications and mutations of CDH1, CTNNB1, VEGFA genes, followed by expression ...
V. A. Tumanskiy   +2 more
doaj   +1 more source

Tau expression and phosphorylation in enteroendocrine cells

open access: yesFrontiers in Neuroscience, 2023
Background and objectiveThere is mounting evidence to suggest that the gut-brain axis is involved in the development of Parkinson’s disease (PD). In this regard, the enteroendocrine cells (EEC), which faces the gut lumen and are connected with both ...
Guillaume Chapelet   +10 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

High fat diet induces microbiota-dependent silencing of enteroendocrine cells

open access: yeseLife, 2019
Enteroendocrine cells (EECs) are specialized sensory cells in the intestinal epithelium that sense and transduce nutrient information. Consumption of dietary fat contributes to metabolic disorders, but EEC adaptations to high fat feeding were unknown ...
Lihua Ye   +5 more
doaj   +1 more source

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