Results 41 to 50 of about 537,505 (139)
Primary and booster immune responses to SA14-14-2 Japanese encephalitis vaccine in Korean infants
, 1999 Attenuated SA14-14-2 Japanese encephalitis (JE) vaccine has been administered safely and effectively to more than 100 million children in China since 1988 and recently, licensure of the vaccine in Korea has been sought.
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Structure-guided design and optimization of small molecules targeting the protein-protein interaction between the von hippel-lindau (VHL) E3 ubiquitin ligase and the hypoxia inducible factor (HIF) alpha subunit with in vitro nanomolar affinities [PDF]
, 2014 E3 ubiquitin ligases are attractive targets in the ubiquitin-proteasome system, however, the development of small-molecule ligands has been rewarded with limited success.
Dias, David M +20 more
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, 1995 Elongation factor-1α (EF-1α) is a highly conserved, abundantly expressed protein that functions in peptide elongation during mRNA translation. Mammalian species contain a second EF-1α gene, S1, whose expression is limited to brain, heart, and skeletal ...
LeBlanc, Andréa +3 more
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VP2 transcription in the different segments of the digestive tract of vaccinated fish.
, 2013 Data are shown as relative transcription levels of VP2 normalized to the transcription of the house-keeping gene EF-1α in fish orally-vaccinated with a VP2 DNA vaccine at day 10 post-vaccination.
Beatriz Abos (421889) +5 more
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PGC-1a in muscle links metabolism to inflammation [PDF]
, 2009 1. In higher eukaryotes, metabolism and immunity are tightly coupled. However, whereas in evolutionary terms, a compromised immune response due to undernourishment has been the predominant problem, the inflammatory response to obesity and other life ...
Handschin, C.
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Characterization of fusion vaccine proteins.
, 2013 a) Schematic overview of homodimeric vaccine proteins. The fusion proteins consists of HA antigen connected to a targeting unit via a shortened Ig hinge and a dimerizing human γ3 CH3 domain and Ig hinge. As targeting units we used a scFv directed against
Gunnveig Grødeland (482642) +4 more
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A VLP-based vaccine against interleukin-1α protects mice from atherosclerosis
, 2013 Interleukin (IL)-1α is a potent proinflammatory cytokine that has been implicated in the development of atherosclerosis. We investigated whether a vaccine inducing IL-1α neutralizing antibodies could interfere with disease progression in a murine model ...
Viesti, Miriam +41 more
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Validation of proteins identified by mass spectrometry analysis.
, 2023 Western blots of human Lyn, Annexin V, GAPDH, and Leishmania fructose bisphosphate aldolase (Ld-aldolase) from autophagosome-enriched fraction four as well as a dot blot of Leishmania EF-1α (Ld-EF-1α) from autophagosome-enriched fraction four (n = 3 ...
Kyung-Mee Moon (685480) +5 more
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, 2019 Translation elongation factor-1alpha (EF-1α) or its paralog elongation factor-like proteins (EFL) interact with an aminoacyl-transfer RNA (aa-tRNA) to play its essential role in elongation of peptide-chain during protein synthesis.
Megumi Kayanuma (1681369) +4 more
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, 2008 Out of 98 subjects who had participated in the 2000 JE vaccination campaign, 69 people were enrolled in the tests of 2004 and 2005 for the evaluation of long term immune response of a single dose of live attenuated SA14-14-2 JE vaccine.
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