Results 111 to 120 of about 52,753 (266)
PLoS ONE, 2015 Efavirenz, a non-nucleoside reverse-transcriptase inhibitor (NNRTI) is one of the most commonly prescribed antiretroviral drugs. The present article provides a systematic overview and meta-analysis of clinical trials comparing efavirenz and other active ...
Joanna Kryst +2 more
doaj +1 more source
Cost and cost-effectiveness of switching from d4T or AZT to a TDF-based first-line regimen in a resource-limited setting in rural Lesotho [PDF]
, 2011 Article approval pendingLatest World Health Organization guidelines recommend shifting away from Stavudine (d4T)-based regimens due to severe side effects.
Bygrave, Helen +11 more
core +2 more sources
Bioenergetics and lipid metabolism in Alzheimer's disease: From cell biology to systemic health
Journal of Internal Medicine, Volume 299, Issue 1, Page 20-43, January 2026.Abstract Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by progressive cognitive decline. Although amyloid‐β and tau pathologies remain central to our understanding of AD, growing evidence suggests that disrupted lipid metabolism and impaired bioenergetics are closely linked to these hallmark features. Genetic, lipidomic
Silvia Maioli +12 more
wiley +1 more source
Infection and Drug Resistance, 2023 Tongtong Wang,1,* Yingchu Liu,2,* Chunyu Zhu,1,* Siyuan Yang,3 Di Yang,4 Jiang Xiao,4 Guiju Gao4 1Beijing Ditan Hospital, Capital Medical University, Beijing, People’s Republic of China; 2School of General Practice and Continuing Education ...
Wang T +6 more
doaj
Efavirenz Intoxication Due to Slow Hepatic Metabolism [PDF]
, 2017 We describe a human immunodeficiency virus-positive woman who presented with severe psychosis while she was receiving therapy with efavirenz. Her plasma efavirenz level was excessively high.
Bleiber, G. +3 more
core
The Doha Round’s Public Health Legacy: Strategies for the Production and Diffusion of Patented Medicines Under the Amended TRIPS Provisions [PDF]
, 2007 This entry into force of the World Trade Organization (WTO) TRIPS Agreement in 1995 transformed the international intellectual property system. The harmonization of basic intellectual property standards has operated to protect investment in innovation ...
Abbott, Frederick M. +1 more
core +2 more sources
Pharmacological Reviews, 2018 Efavirenz is a highly effective HIV-1 antiretroviral; however, it is also frequently associated with neuropsychiatric adverse events (NPAE) that include abnormal dreams, sleep disturbances, nervousness, anxiety, depression, and dizziness.
Dhwanil A. Dalwadi +4 more
semanticscholar +1 more source
Era of direct acting anti-viral agents for the treatment of hepatitis C. [PDF]
, 2018 Hepatitis C infection is universal and the most common indication of liver transplantation in the United States. The period of less effective interferon therapy with intolerable side effects has gone.
Ahmed, Monjur
core +1 more source
The utility of efavirenz-based prophylaxis against HIV infection. A systems pharmacological analysis [PDF]
, 2019 Pre-exposure prophylaxis (PrEP) is considered one of the five “pillars” by UNAIDS to reduce HIV transmission. Moreover, it is a tool for female self-protection against HIV, making it highly relevant to sub-Saharan regions, where women have the highest ...
Dickinson, Laura +4 more
core +4 more sources
HIV Medicine, 2018 The single‐tablet regimen rilpivirine, emtricitabine and tenofovir alafenamide (RPV/FTC/TAF) for treatment of HIV‐1‐infected adults was approved based on bioequivalence.
D. Hagins +18 more
semanticscholar +1 more source