Results 91 to 100 of about 28,830 (241)

Pharmacogenetic & pharmacokinetic biomarker for efavirenz based ARV and rifampicin based anti-TB drug induced liver injury in TB-HIV infected patients.

open access: yesPLoS ONE, 2011
BackgroundImplication of pharmacogenetic variations and efavirenz pharmacokinetics in concomitant efavirenz based antiviral therapy and anti-tubercular drug induced liver injury (DILI) has not been yet studied.
Getnet Yimer   +10 more
doaj   +1 more source

Antiretroviral treatment in HIV-1 infected pediatric patients: focus on efavirenz

open access: yesPediatric Health, Medicine and Therapeutics, 2014
Beatriz Larru,1 Jessica Eby,2,3 Elizabeth D Lowenthal2,4,51Department of Pediatrics, Division of Infectious Diseases, 2Department of Pediatrics, Division of General Pediatrics, Children's Hospital of Philadelphia, Philadelphia, 3Villanova University,
Larru B, Eby J, Lowenthal ED
doaj  

Development and validation of a HPLC analytical assay method for efavirenz tablets: a medicine for HIV infections

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2011
Efavirenz is a reverse transcriptase non analog nucleoside inhibitor used to treat HIV infections. A simple assay method by high performance liquid chromatography was developed and validated for efavirenz tablets. The physical chemical characteristics of
Osnir de Sá Viana   +9 more
doaj   +1 more source

O Efavirenz: Relação Estrutura-Atividade e Métodos de Síntese [PDF]

open access: green, 2015
Carolina C. P. Costa   +4 more
openalex   +1 more source

Comparison efavirenz pharmacokinetics between DILI cases and controls: mean log transformed plasma efavirenz (ng/mL).

open access: yes, 2013
8-hydroxyefavirenz (ng/mL) and efavirenz/8-hydroxyefavirenz ratio (MR) was compared between patients who developed concomitant efavirenz-based HAART and rifampicin based anti-tubercular drugs induced liver injury (cases) and those who did not (controls).
Lars Lindquist (316252)   +10 more
core   +1 more source

Efavirenz Induced Suicidal Death of Human Erythrocytes [PDF]

open access: yes, 2015
Background/Aims: The reverse transcriptase inhibitor efavirenz utilized for the treatment of human immunodeficiency virus (HIV)-1 infection, triggers suicidal cell death or apoptosis, an effect in part due to interference with mitochondrial potential ...
Abdulla Al Mamun Bhuyan   +5 more
core   +1 more source

Efavirenz Plasma Concentrations and Cytochrome 2B6 Polymorphisms

open access: yes, 2010
Background: Interpatient variability in efavirenz concentrations may be due to CYP2B6 genetic polymorphisms. Efavirenz concentration and pharmacogenomic data are scarce in Latino patients.
Jessica C Song   +4 more
core   +1 more source

Development and Validation of a LC-MS/MS Assay for the Quantification Of Efavirenz In Different Biological Matrices

open access: yes, 2016
Aim: The non-nucleoside reverse transcriptase inhibitor efavirenz is one of the most prescribed antiretroviral therapeutics. Efavirenz-containing therapy has become associated with the occurrence of CNS side effects, including sleep disturbances ...

core   +1 more source

Simplification of therapy (ART) with efavirenz/emtricitabine/tenofovir DF single tablet regimen vs. continued ART in suppressed, HIV-infected patients [PDF]

open access: gold, 2008
Benjamin Young   +8 more
openalex   +1 more source

Home - About - Disclaimer - Privacy