Results 91 to 100 of about 28,830 (241)
BackgroundImplication of pharmacogenetic variations and efavirenz pharmacokinetics in concomitant efavirenz based antiviral therapy and anti-tubercular drug induced liver injury (DILI) has not been yet studied.
Getnet Yimer +10 more
doaj +1 more source
Antiretroviral treatment in HIV-1 infected pediatric patients: focus on efavirenz
Beatriz Larru,1 Jessica Eby,2,3 Elizabeth D Lowenthal2,4,51Department of Pediatrics, Division of Infectious Diseases, 2Department of Pediatrics, Division of General Pediatrics, Children's Hospital of Philadelphia, Philadelphia, 3Villanova University,
Larru B, Eby J, Lowenthal ED
doaj
Efavirenz is a reverse transcriptase non analog nucleoside inhibitor used to treat HIV infections. A simple assay method by high performance liquid chromatography was developed and validated for efavirenz tablets. The physical chemical characteristics of
Osnir de Sá Viana +9 more
doaj +1 more source
A Potentially Significant Interaction between Efavirenz and Phenytoin: A Case Report and Review of the Literature [PDF]
Sarah Robertson +4 more
openalex +1 more source
O Efavirenz: Relação Estrutura-Atividade e Métodos de Síntese [PDF]
Carolina C. P. Costa +4 more
openalex +1 more source
8-hydroxyefavirenz (ng/mL) and efavirenz/8-hydroxyefavirenz ratio (MR) was compared between patients who developed concomitant efavirenz-based HAART and rifampicin based anti-tubercular drugs induced liver injury (cases) and those who did not (controls).
Lars Lindquist (316252) +10 more
core +1 more source
Efavirenz Induced Suicidal Death of Human Erythrocytes [PDF]
Background/Aims: The reverse transcriptase inhibitor efavirenz utilized for the treatment of human immunodeficiency virus (HIV)-1 infection, triggers suicidal cell death or apoptosis, an effect in part due to interference with mitochondrial potential ...
Abdulla Al Mamun Bhuyan +5 more
core +1 more source
Efavirenz Plasma Concentrations and Cytochrome 2B6 Polymorphisms
Background: Interpatient variability in efavirenz concentrations may be due to CYP2B6 genetic polymorphisms. Efavirenz concentration and pharmacogenomic data are scarce in Latino patients.
Jessica C Song +4 more
core +1 more source
Aim: The non-nucleoside reverse transcriptase inhibitor efavirenz is one of the most prescribed antiretroviral therapeutics. Efavirenz-containing therapy has become associated with the occurrence of CNS side effects, including sleep disturbances ...
core +1 more source
Simplification of therapy (ART) with efavirenz/emtricitabine/tenofovir DF single tablet regimen vs. continued ART in suppressed, HIV-infected patients [PDF]
Benjamin Young +8 more
openalex +1 more source

