Results 61 to 70 of about 6,293,610 (293)

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Application of Graph Theory for Identifying Connectivity Patterns in Human Brain Networks: A Systematic Review

Frontiers in Neuroscience, 2019
Background: Analysis of the human connectome using functional magnetic resonance imaging (fMRI) started in the mid-1990s and attracted increasing attention in attempts to discover the neural underpinnings of human cognition and neurological disorders. In
Farzad V. Farahani, Waldemar Karwowski, Nichole R. Lighthall   +2 more
doaj   +1 more source

Dysfunction in the Interaction of Information Between and Within the Bilateral Primary Sensory Cortex

Frontiers in Aging Neuroscience, 2022
BackgroundInterhemispheric and intrahemispheric long-range synchronization and information communication are crucial features of functional integration between the bilateral hemispheres.
Xiang-Xin Xing, Xiang-Xin Xing, Xiang-Xin Xing, Zhen-Zhen Ma, Zhen-Zhen Ma, Jia-Jia Wu, Jia-Jia Wu, Jie Ma, Jie Ma, Yu-Jie Duan, Yu-Jie Duan, Xu-Yun Hua, Xu-Yun Hua, Mou-Xiong Zheng, Mou-Xiong Zheng, Jian-Guang Xu, Jian-Guang Xu   +16 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Effective connectivity.

, 2013
When viewing appetizing versus bland foods, the effective connectivity between right caudate nucleus and right amygdala (AMY), insula (INS) and somatosensory cortex (SSC) was greater in obese than in normal-weight subjects.
Lauri Nummenmaa (196039), Jarna C. Hannukainen (333568), Paulina Salminen (333571), Pirjo Nuutila (181289), Jussi Hirvonen (203774), Heidi Immonen (333569), Markus M. Lindroos (333570)   +6 more
core   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Individual differences in white matter microstructure reflect variation in functional connectivity during action choice. [PDF]

, 2007
The relation between brain structure and function is of fundamental importance in neuroscience. Comparisons between behavioral and brain imaging measures suggest that variation in brain structure correlates with the presence of specific skills[1-3 ...
Sebastian, C, Johansen-Berg, H, O Shea, J, Boorman, ED, Rushworth, MFS   +4 more
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

The effective connectivity of the human hippocampal memory system

, 2022
Effective connectivity measurements in the human hippocampal memory system based on the resting-state blood oxygenation-level dependent signal were made in 172 participants in the Human Connectome Project to reveal the directionality and strength of the ...
Feng, Jianfeng, Deco, Gustavo, Huang, Chu-Chung, Rolls, Edmund T., Jianfeng Feng, Edmund T Rolls, Gustavo Deco, Chu-Chung Huang   +7 more
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source