Results 221 to 230 of about 7,654,241 (295)

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Robust biexciton preparation for entangled photon-pair generation by single-shot Floquet driving. [PDF]

open access: yesNat Commun
Yan JY   +14 more
europepmc   +1 more source

Air conditioning and the future electricity system in Great Britain. [PDF]

open access: yesEnergy Res Soc Sci
Simpson CH   +5 more
europepmc   +1 more source

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