Results 111 to 120 of about 5,522,348 (307)

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Drying and Rehydration of Sullius luteus Under Different Pretreatments: Kinetic Modeling, Rehydration, and Chromatic Changes

Applied Sciences
Edible mushrooms (Suillus luteus) represent valuable sources of nutrients and bioactive compounds that are sensitive to drying conditions. The objective of this study was to determine the drying time, kinetic model, effective diffusivity, activation ...
Alfredo Fernandez-Ayma, Víctor Justiniano Huamaní-Meléndez, Luis Fernando Pérez-Falcón, Franklin Lozano, Guadalupe Chaquilla-Quilca   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dynamic Modeling of Convective Drying of Pineapple Peels: Bioactive, Physical, and Thermal Properties

Agriculture
The fruit processing agroindustry generates waste, mainly composed of peels, which are often discarded but can be utilized as ingredients for developing new food products.
Raniza de Oliveira Carvalho, Rossana Maria Feitosa de Figueirêdo, Alexandre José de Melo Queiroz, Francislaine Suelia dos Santos, Mailson Gonçalves Gregório, Lumara Tatiely Santos Amadeu, Henrique Valentim Moura, Nailton de Macedo Albuquerque Junior, Fabrícia Santos Andrade, Emily Bezerra Coutinho Cruz, Emerson Zambrano Lara, Josivanda Palmeira Gomes, Marta Suely Madruga   +12 more
doaj   +1 more source

Cinética de secagem de folhas de Solanum lycocarpum A. St.-Hil. (fruta-de-lobo) Drying kinetics of leaves of Solanum lycocarpum A. St.-Hil. (wolf apple)

Revista Brasileira de Plantas Medicinais, 2012
Objetivou-se neste trabalho determinar o tempo de secagem e modelar as curvas de secagem de folhas de fruta-de-lobo (Solanum lycocarpum A. St.-Hil.) secas em temperaturas de 40, 50 e 60ºC, num secador de leito fixo em camada fina com velocidade do ar de ...
M.F.O. Prates, R.C. Reis, I.A. Devilla, R.Q. Faria, A.F. Lima Junior   +4 more
doaj   +1 more source

Effective Diffusivity of Carbon Dioxide and Iodine through “G” Tunnel Tuff

, 1989
The effective diffusivity of carbon dioxide and iodine through “G” tunnel tuff were determined using a steady-state method and an unsteady-state method respectively.
Tevfik Bardakci, Franklin G. King, Maung K. Sein   +2 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Brownian yet Non-Gaussian Diffusion: From Superstatistics to Subordination of Diffusing Diffusivities

Physical Review X, 2017
A growing number of biological, soft, and active matter systems are observed to exhibit normal diffusive dynamics with a linear growth of the mean-squared displacement, yet with a non-Gaussian distribution of increments.
Aleksei V. Chechkin, Flavio Seno, Ralf Metzler, Igor M. Sokolov   +3 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source