Results 41 to 50 of about 7,042,121 (243)

Study on the Sensitivity of Gas Extraction Parameters and the Dynamic Evolution of the Effective Extraction Radius Under Multiphysics Coupling

Energies
To investigate the sensitivity and underlying mechanisms of key parameters for gas extraction, a three-dimensional numerical model was established. Using the control variable method, the effects of critical extraction parameters on gas pressure evolution,
Huogen Luo, Qianting Hu
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Morphological Characteristics of Hydraulic Flushing under Multifactor Coupling and Its Enlightenment

Geofluids, 2022
The shape of the hydraulic flushing hole is an important basis to determine the effective pumping radius. In the design and evaluation of the drilling hole, it is usually equivalent to a cylinder.
Xiao Liu, Tianxiang Jing, Dequan Xuan, Shixiong Hu, Yong Li, Sen Xu   +5 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Accurate nucleon electromagnetic form factors from dispersively improved chiral effective field theory

Physics Letters B, 2018
We present a theoretical parametrization of the nucleon electromagnetic form factors (FFs) based on a combination of chiral effective field theory and dispersion analysis.
J.M. Alarcón, C. Weiss
doaj   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

FEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa, Mohammed Nooh, Akhil Geddati, Alex Dopico, Anna N. Bukiya   +4 more
wiley   +1 more source

Study on influence of superimposed effect of gas extraction in downhole drilling

Meitan kexue jishu
In order to better reveal the change of effective extraction radius and the influence of extraction superposition effect on the extraction effect in the process of coal seam gas extraction, a three-dimensional coal seam gas-solid coupling model is ...
Jun LIU, Peng LU, Zhikuan LIU, Min SU
doaj   +1 more source

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino, Lavanya Muthukumar, Evan L. Reynolds, Peter Todd, Sinem Ovunc, Sheng Chih Jin, Zitian Tang, Simone Thomas, PNRR Study Group, Ahmet Höke, Brian C. Callaghan, Sarah Berth, Vinay Chaudhry, David Cornblath, Leana Doherty, Lindsey Hayes, Hristelina Ilieva, Thomas Lloyd, Mohammad Khoshnoodi, Brett McCray, Brett Morrison, Bipasha Mukherjee‐Clavin, Lyle Ostrow, Michael Polydefkis, Ricardo Roda, Charlotte Sumner   +25 more
wiley   +1 more source

Optimization and Application of Drilling Parameters Based on Gas–Solid Coupling Simulation

Applied Sciences
The layout of directional high-level long boreholes in fracture zones for extracting pressure-relieved gas from goaf is a key technology to address the gas concentration exceedance in upper corners.
Zhiguo Ge, Guochao Yan, Shaoqi Kong, Baodong Zong, Huizhi Liu, Jinjing Huang, Gaochuan Guo   +6 more
doaj   +1 more source