Results 31 to 40 of about 41,310 (228)

Leukemia and Exposure to Potential Benzene Sources in Children From the Mexico City Metropolitan Area, 2010–2021: A Geospatial Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Leukemia is the most common childhood cancer in Mexico, and acute lymphoblastic leukemia (ALL) is the most frequent subtype. Exposure to high concentrations of benzene has been associated with ALL incidence, particularly in urban areas. This study evaluated the relationship between distance to benzene emission sources and the number
Orlando Rivera Zurita   +5 more
wiley   +1 more source

Response Characteristics of Coal-Like Material Subjected to Repeated Hydraulic Fracturing: An Evaluation Based on Real-Time Monitoring of Water Injection Pressure and Roof Stress Distribution

open access: yesShock and Vibration, 2021
Conventional hydraulic fracturing has several disadvantages, including a short effective extraction time and low fracture conductivity during long-term extraction.
Yongjiang Zhang   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Research on pre-pumping gas control technology for large-diameter borehole

open access: yes矿业科学学报
The large quarry face with a strike length of 3 300 m in Sijiazhuang Mine features high gas reserve, large gas outflow and its upper corner is easy to exceed the limit.This study adopts the gas management technology of extracting the gas from the coal ...
XIE Jun
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Study on the Sensitivity of Gas Extraction Parameters and the Dynamic Evolution of the Effective Extraction Radius Under Multiphysics Coupling

open access: yesEnergies
To investigate the sensitivity and underlying mechanisms of key parameters for gas extraction, a three-dimensional numerical model was established. Using the control variable method, the effects of critical extraction parameters on gas pressure evolution,
Huogen Luo, Qianting Hu
doaj   +1 more source

Morphological Characteristics of Hydraulic Flushing under Multifactor Coupling and Its Enlightenment

open access: yesGeofluids, 2022
The shape of the hydraulic flushing hole is an important basis to determine the effective pumping radius. In the design and evaluation of the drilling hole, it is usually equivalent to a cylinder.
Xiao Liu   +5 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

open access: yesFEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring   +3 more
wiley   +1 more source

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