Results 121 to 130 of about 1,411,743 (333)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Field redefinitions can be nonlocal

open access: yesJournal of High Energy Physics
We revisit the lore establishing the allowed space of field redefinitions and show that there are essentially no restrictions. Our conclusions hold to all orders in perturbation theory and for any dispersion relation. Field redefinitions can be nonlocal,
Timothy Cohen   +2 more
doaj   +1 more source

Testing symmetries in effective models of higher derivative field theories

open access: yes, 2009
Higher derivative field theories with interactions raise serious doubts about their validity due to severe energy instabilities. In many cases the implementation of a direct perturbation treatment to excise the dangerous negative-energies from a higher ...
A. A. Slavnov   +4 more
core   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Perturbiner Methods for Effective Field Theories and the Double Copy

open access: yes, 2018
Perturbiner expansion provides a generating function for all Berends-Giele currents in a given quantum field theory. We apply this method to various effective field theories with and without color degrees of freedom. In the colored case, we study the U(N)
Mizera, Sebastian, Skrzypek, Barbara
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Effective field theory and χpt [PDF]

open access: yesAIP Conference Proceedings, 2000
A brief introduction to the subject of chiral perturbation theory ($\chi$pt) is given, including a discussion of effective field theory and application to the upcoming Bates virtual Compton scattering measurement.
openaire   +2 more sources

Low Energy Effective Field Theories of Sp(4) Spin systems

open access: yes, 2009
We study the classical and quantum phase transitions of Sp(4) spin systems on three dimensional stacked square and triangular lattices. We present general Ginzburg-Landau field theories for various types of Sp(4) spin orders with different ground state ...
Cenke Xu, M. Nakahara
core   +1 more source

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