Results 131 to 140 of about 1,411,743 (333)
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Effective field theory in the top sector: Do multijets help? [PDF]
, 2019 Christoph Englert +2 more
openalex +1 more source
An Introduction to Effective Field Theory [PDF]
Annual Review of Nuclear and Particle Science, 2007 This review summarizes effective field theory techniques, which are the modern theoretical tools for exploiting the existence of hierarchies of scale in a physical problem. The general theoretical framework is described and evaluated explicitly for a simple model. Power-counting results are illustrated for a few cases of practical interest, and several
openaire +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Threshold resummation for semi-inclusive single-hadron production with effective field theory
Journal of High Energy PhysicsLarge double-logarithmic corrections are induced by soft gluon emissions near threshold in the semi-inclusive e + e − annihilation (SIA) distributions, and must be resummed to all-orders in perturbation theory for reliable theoretical predictions ...
Zhen Xu, Hua Xing Zhu
doaj +1 more source
Scale-Chiral Effective Field Theory for Nuclear Interactions in the Veneziano Limit [PDF]
, 2018 Yanling Li +3 more
openalex +1 more source
Background Field Method and Generalized Field Redefinitions in Effective Field Theories [PDF]
, 2021 Andrea Quadri
openalex +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source