Results 61 to 70 of about 96,106 (310)

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Manifestly SL(2, R) Duality-Symmetric Forms in ModMax Theory

Journal of High Energy Physics, 2022
In this paper, we will investigate a manifestly SL(2, R)-invariant structure for the energy-momentum tensor of ModMax theory as a nonlinear modification of Maxwell electrodynamics which includes conformal invariance as well. In the context of this theory,
H. Babaei-Aghbolagh, Komeil Babaei Velni, Davood Mahdavian Yekta, H. Mohammadzadeh   +3 more
doaj   +1 more source

Effective field theory for magnetic compactifications [PDF]

Journal of High Energy Physics, 2017
Magnetic flux plays an important role in compactifications of field and string theories in two ways, it generates a multiplicity of chiral fermion zero modes and it can break supersymmetry. We derive the complete four-dimensional effective action for N=1 supersymmetric Abelian and non-Abelian gauge theories in six dimensions compactified on a torus ...
Buchmuller, Wilfried, Dierigl, Markus, Dudas, Emilian, Schweizer, Julian   +3 more
openaire   +7 more sources

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

On the species scale, modular invariance and the gravitational EFT expansion

Journal of High Energy Physics
The concept of the species scale as the quantum gravity cut-off has been recently emphasised in the context of the Swampland program. Along these lines, we continue the quest for a precise understanding of its role within effective field theories of ...
A. Castellano, A. Herráez, L. E. Ibáñez   +2 more
doaj   +1 more source

Conformal bootstrap at large charge

Journal of High Energy Physics, 2018
We consider unitary CFTs with continuous global symmetries in d > 2. We consider a state created by the lightest operator of large charge Q ≫ 1 and analyze the correlator of two light charged operators in this state.
Daniel Jafferis, Baur Mukhametzhanov, Alexander Zhiboedov   +2 more
doaj   +1 more source

Whence the Effectiveness of Effective Field Theories? [PDF]

The British Journal for the Philosophy of Science, 2020
Effective Quantum Field Theories (EFTs) are effective insofar as they apply within a prescribed range of length-scales, but within that range they predict and describe with extremely high accuracy and precision. The effectiveness of EFTs is explained by identifying the features – the scaling behaviour of the parameters – which lead to effectiveness ...
openaire   +5 more sources

Effective field theory of cosmological perturbations [PDF]

Classical and Quantum Gravity, 2013
The effective field theory of cosmological perturbations stems from considering a cosmological background solution as a state displaying spontaneous breaking of time translations and (adiabatic) perturbations as the related Nambu-Goldstone modes. With this insight, one can systematically develop a theory for the cosmological perturbations during ...
Piazza, Federico, Vernizzi, Filippo
openaire   +5 more sources

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source

Inverse bootstrapping conformal field theories

Journal of High Energy Physics, 2018
We propose a novel approach to study conformal field theories (CFTs) in general dimensions. In the conformal bootstrap program, one usually searches for consistent CFT data that satisfy crossing symmetry.
Wenliang Li
doaj   +1 more source