Results 131 to 140 of about 20,171,588 (326)

Effective population size in field pea

open access: yesBMC Genomics
Background Effective population size (N e ) is a pivotal parameter in population genetics as it can provide information on the rate of inbreeding and the contemporary status of genetic diversity in breeding populations.
Josephine Princy Johnson   +7 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Inbreeding depression in maize populations of reduced size

open access: yesScientia Agricola, 2002
Inbreeding is a well known phenomenon in living beings and its immediate consequence is the decrease in the expression of quantitative traits, known as inbreeding depression.
Félix Alonso Astete Maldonado   +1 more
doaj  

Effective Sample Size for Importance Sampling based on discrepancy measures

open access: yes, 2016
The Effective Sample Size (ESS) is an important measure of efficiency of Monte Carlo methods such as Markov Chain Monte Carlo (MCMC) and Importance Sampling (IS) techniques.
Elvira, V., Louzada, F., Martino, L.
core   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Long- and short-range correlations in the ab-initio no-core shell model

open access: yes, 2006
In the framework of the ab-initio no-core shell model (NCSM), we describe the longitudinal-longitudinal distribution function, part of the inclusive (e,e') longitudinal response.
Barrett, Bruce R.   +3 more
core   +2 more sources

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