Results 61 to 70 of about 7,592,081 (289)

Alternative life‐history strategy contributions to effective population size in a naturally spawning salmon population

open access: yesEvolutionary Applications, 2023
Alternative life‐history tactics are predicted to affect within‐population genetic processes but have received little attention. For example, the impact of precocious males on effective population size (Ne) has not been quantified directly in Pacific ...
Erika King   +5 more
doaj   +1 more source

CPX‐351 in High‐Risk Relapsed Pediatric Acute Leukemia: Real‐World Phase 1 Data Establishing the FDA‐Approved Dose

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Outcomes for pediatric relapsed/refractory (R/R) acute myeloid leukemia (AML) remain dismal. CPX‐351, a liposomal formulation of cytarabine and daunorubicin, may have less off‐target toxicities than traditional chemotherapies and has shown improved outcomes for adults with newly diagnosed therapy‐related AML.
Jonathan D. Bender   +17 more
wiley   +1 more source

Effective number of white shark (Carcharodon carcharias, Linnaeus) breeders is stable over four successive years in the population adjacent to eastern Australia and New Zealand

open access: yesEcology and Evolution, 2021
Population size is a central parameter for conservation; however, monitoring abundance is often problematic for threatened marine species. Despite substantial investment in research, many marine species remain data‐poor presenting barriers to the ...
Danielle Davenport   +5 more
doaj   +1 more source

Incidence and Risk Factors of Serious Osteonecrosis in Pediatric Acute Lymphoblastic Leukemia: A CYP‐C Population‐Based Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteonecrosis (ON) is a debilitating complication of acute lymphoblastic leukemia (ALL) therapy. While numerous studies have explored its incidence and associated risk factors, investigations using large‐scale cohorts remain important to characterize ON across heterogeneous populations.
Noémie de Villiers   +5 more
wiley   +1 more source

Exploring the genetic features and signatures of selection in South China indigenous pigs

open access: yesJournal of Integrative Agriculture, 2021
To explore the genetic features and signatures of selection in indigenous pigs from South China and Duroc pigs, 259 pigs from six populations were genotyped using single-nucleotide polymorphism (SNP) BeadChips.
Shu-qi DIAO   +9 more
doaj   +1 more source

Improving the Evaluation and Management of Transfusion‐Related Iron Overload in Children, Adolescents, and Young Adults Following Cancer Treatment or Hematopoietic Stem Cell Transplantation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Transfusion‐related iron overload (TRIO) is a late effect of therapy impacting survivors of childhood cancer and hematopoietic stem cell transplantation (HSCT) who receive frequent packed red blood cell (pRBC) transfusions. Surprisingly, there are no accepted guidelines to assist providers in identifying and treating at‐risk ...
Luke Gingell   +3 more
wiley   +1 more source

Entanglement in low-energy states of the random-hopping model [PDF]

open access: yes, 2014
We study the low-energy states of the 1D random-hopping model in the strong disordered regime. The entanglement structure is shown to depend solely on the probability distribution for the length of the effective bonds $P(l_b)$, whose scaling and finite ...
Ramírez, Giovanni   +2 more
core   +2 more sources

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack   +39 more
wiley   +1 more source

16 Years of breed management brings substantial improvement in population genetics of the endangered Cleveland Bay Horse

open access: yesEcology and Evolution, 2021
The consequences of poor breed management and inbreeding can range from gradual declines in individual productivity to more serious fertility and mortality concerns.
Andrew Dell   +6 more
doaj   +1 more source

Effective Sample Size: Quick Estimation of the Effect of Related Samples in Genetic Case-Control Association Analyses [PDF]

open access: yes, 2007
Correlated samples have been frequently avoided in case-control genetic association studies in part because the methods for handling them are either not easily implemented or not widely known.
Chukwuma Ogunwole   +5 more
core   +1 more source

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