Results 81 to 90 of about 3,043,757 (303)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The effect of population structure, plant size, herbivory and reproductive potential on effective population size in the temperate epiphytic orchid, Sarcochilus australis

open access: yes, 2013
Distribution of plant size and reproductive success is investigated in the temperate epiphytic orchid Sarcochilus australis (Lindl.) Rchb. f. at Kinglake National Park, Victoria, in south-eastern Australia, and applied to estimating the effective ...
Tremblay, Raymond L.
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

AS-270-88 Resolution on the Effects of Class Size, Mode and Level of Faculty Workload

open access: yes, 1988
Recommends department consultation regarding workload, class size, etc.
Ad Hoc Committee on Effective Class Size, Instructional Quality, and Faculty Workload,
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Effective population size.

open access: yes, 2018
Effective population size Ne by watershed, where steelhead collections are in crosshatch pattern. * indicates the NE estimate was infinity.
Erik Lesko (5101352)   +6 more
core   +1 more source

Effective population sizes in cattle, sheep, horses, pigs and goats estimated from census and herdbook data

open access: yesAnimal, 2016
Accurate measures of effective population sizes (Ne) in livestock require good quality data and specialized skills for their computation and analysis. Ne can be estimated by Wright’s equation Ne=4MF/(M+ F) (M, F being sires and dams, respectively), but ...
S.J.G. Hall
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Influence of particle-size distribution on effective properties of nanocomposites

open access: yes, 2008
Classical micromechanics methods in predicting the effective properties of particle-filled composites do not admit the size dependence of particles. However, when particle sizes are in the nanometer range, the surface/interface energy effect will become ...
Wang ZQ, Huang ZP, 赵亚溥, Wang J
core  

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