Assessment of the Global Variance Effective Size of Subdivided Populations, and Its Relation to Other Effective Sizes. [PDF]
Hössjer O, Laikre L, Ryman N.
europepmc +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Temporal moment-based effective genetic size estimates.
NG = number of generations between a pair of samples. Ne = effective genetic size estimate. Lower and upper 95% CI represents a 95% Confidence Interval (CI) for Ne estimated for each pair of samples. Ne/Nc ratio = ratio between effective population size (
Tatiana Fioravanti (2609869) +12 more
core +1 more source
Effective Size Reduction of the Metallic Waveguide Bandpass Filter with Metamaterial Resonators and Its 3D-Printed Version. [PDF]
Cho J +6 more
europepmc +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Effective population size in field pea
Background Effective population size (N e ) is a pivotal parameter in population genetics as it can provide information on the rate of inbreeding and the contemporary status of genetic diversity in breeding populations.
Josephine Princy Johnson +7 more
doaj +1 more source
Heterogeneity in effective size across the genome: effects on the inverse instantaneous coalescence rate (IICR) and implications for demographic inference under linked selection. [PDF]
Boitard S +3 more
europepmc +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Effective size in simple metapopulation models
International audienceA coalescent argument is used to derive the effective size in simple models with recurrent local extinctions. Several alternative methods of derivation of this result are given and compared to earlier analyses of this problem.
F Rousset, Rousset, Francois
core +1 more source
Recent human effective population size estimated from linkage disequilibrium [PDF]
Effective population size (N(e)) determines the amount of genetic variation, genetic drift, and linkage disequilibrium (LD) in populations. Here, we present the first genome-wide estimates of human effective population size from LD data.
Tenesa, Albert +12 more
core +1 more source

