Results 61 to 70 of about 1,639,498 (342)
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
The hadronic off-shell width of meson resonances [PDF]
, 2000 Within the resonance chiral effective theory we study the dressed propagators of the spin-1 fields, as arise from a Dyson-Schwinger resummation perturbatively constructed from loop diagrams with absorptive contributions in the s-channel.
Dumm, D. Gomez, Pich, A., Portoles, J.
core +4 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Preliminary lattice study of $\sigma$ meson decay width
, 2012 We report an exploratory lattice investigation of $\sigma$ meson decay width using s-wave scattering phase for isospin I=0 pion-pion ($\pi\pi$) system. Rummukainen-Gottlieb formula is used to estimate the scattering phase, which demonstrate the presence ...
Fu, Ziwen
core +1 more source
Surface effect on domain wall width in ferroelectrics [PDF]
Journal of Applied Physics, 2009 We study the effect of the depolarization field on a domain wall structure near the surface of a ferroelectric. Since in real situation bound and screening charges form an electric double layer, the breaking of this layer by the domain wall induces stray depolarization field, which in turn changes the domain wall structure. Power law decay of the stray
Eliseev, Eugene A. +7 more
openaire +2 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Effective width estimation of flanged reinforced concrete shear walls [PDF]
, 2023 Mohammad Tabiee +3 more
openalex +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
An effective rolling process of magnesium alloys for suppressing edge cracks: Width-limited rolling
Journal of Magnesium and Alloys, 2022 To suppress the edge crack of the magnesium alloy sheet during the ordinary rolling process, a new rolling process named width-limited rolling was proposed in this paper.
Jing Tian +7 more
doaj +1 more source