Results 41 to 50 of about 18,481,212 (402)
Structures of Phytophthora RXLR Effector Proteins: a conserved but adaptable fold underpins functional diversity [PDF]
Phytopathogens deliver effector proteins inside host plant cells to promote infection. These proteins can also be sensed by the plant immune system, leading to restriction of pathogen growth.
Adams+49 more
core +1 more source
Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
Innate immunity provides the first line of defence against invading pathogens and provides important cues for the development of adaptive immunity. Type-2 immunity—responsible for protective immune responses to helminth parasites and the underlying cause
D. R. Neill+11 more
semanticscholar +1 more source
Molecular signatures distinguish human central memory from effector memory CD8 T cell subsets [PDF]
Memory T cells are heterogeneous in terms of their phenotype and functional properties. We investigated the molecular profiles of human CD8 naive central memory (TCM), effector memory (TEM), and effector memory RA (TEMRA) T cells using gene expression ...
Callan, Margaret F C+4 more
core +1 more source
GEF-effector interactions [PDF]
Members of the Arf family of small GTP-binding proteins, or GTPases, are activated by guanine nucleotide exchange factors (GEFs) that catalyze GDP release from their substrate Arf, allowing GTP to bind. In the secretory pathway, Arf1 is first activated by GBF1 at the cis-Golgi, then by BIG1 and BIG2 at the trans-Golgi and trans-Golgi network (TGN ...
openaire +3 more sources
Gasdermins: Effectors of Pyroptosis [PDF]
Pyroptosis is a form of lytic programmed cell death initiated by inflammasomes, which detect cytosolic contamination or perturbation. This drives activation of caspase-1 or caspase-11/4/5, which cleave gasdermin D, separating its N-terminal pore-forming domain (PFD) from the C-terminal repressor domain (RD).
Stephen B. Kovacs, Edward A. Miao
openaire +3 more sources
T-Bet and Eomes Regulate the Balance between the Effector/Central Memory T Cells versus Memory Stem Like T Cells [PDF]
Memory T cells are composed of effector, central, and memory stem cells. Previous studies have implicated that both T-bet and Eomes are involved in the generation of effector and central memory CD8 T cells.
A Banerjee+36 more
core +7 more sources
Transcription factor-based biosensors enlightened by the analyte.
Whole cell biosensors (WCBs) have multiple applications for environmental monitoring, detecting a wide range of pollutants. WCBs depend critically on the sensitivity and specificity of the transcription factor (TF) used to detect the analyte.
Raul eFernandez-Lopez+3 more
doaj +1 more source
Plant immune receptors interact with hemibiotrophic pathogens to activate plant immunity
Phytopathogens pose a devastating threat to the productivity and yield of crops by causing destructive plant diseases in natural and agricultural environments.
Diao Zhou+17 more
doaj +1 more source
Apoplastic interactions between plants and plant root intruders
Numerous pathogenic or parasitic organisms attack plant roots to obtain nutrients, and the apoplast including the plant cell wall is where the plant cell meets such organisms.
Kanako eMitsumasu+2 more
doaj +1 more source
Bradyrhizobium elkanii USDA61 is incompatible with mung bean (Vigna radiata cv. KPS1) and soybean (Glycine max cv. BARC2) and unable to nodulate either plant.
Hien P. Nguyen+5 more
doaj +1 more source