Results 251 to 260 of about 2,174,249 (299)
Some of the next articles are maybe not open access.
Pyroptosis modulation by bacterial effector proteins
Seminars in Immunology, 2023Pyroptosis is a proinflammatory form of programmed cell death featured with membrane pore formation that causes cellular swelling and allows the release of intracellular inflammatory mediators. This cell death process is elicited by the activation of the pore-forming proteins named gasdermins, and is intricately orchestrated by diverse regulatory ...
Qiyao Chai, Zehui Lei, Cui Hua Liu
openaire +2 more sources
Proteins as Biological Effectors
2017This chapter presented an overview of the role of proteins as biological effectors. From a simplistic point of view, based solely on comparison of the structural diversity of immunoglobulins, blood coagulation proteins, gonadotropins, growth factors, and antiproteins, it could be concluded that the functional mechanisms of these protein families bear ...
M T, Hearn, P G, Stanton, J, Bertolini
openaire +2 more sources
Effector proteins of chlamydiae
Molecular Biology, 2009This review summarizes the recently published data on the molecular mechanisms of Chlamydiae-host cell interaction, first of all, on chlamydial effector proteins. Such proteins, along with type III transport system proteins, which transfer many effector proteins into the host cytoplasm, are attractive targets for drug therapy of chlamydial infections ...
A. S. Karyagina +4 more
openaire +1 more source
Interactions of bacterial effector proteins with host proteins
Current Opinion in Immunology, 2007Pathogenic bacteria have evolved several clever survival strategies for manipulating host cell signaling pathways to establish beneficial replicative niches within the host. Recent literature has revealed novel mechanisms adopted by bacteria to manipulate host responses.
Seema, Mattoo +2 more
openaire +2 more sources
Receptor-effector coupling by G proteins
Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1990The primary structure of G proteins as deduced from purified proteins and cloned subunits is presented. When known, their functions are discussed, as are recent data on direct regulation of ionic channels by G proteins. Experiments on expression of alpha subunits, either in bacteria or by in vitro translation of mRNA synthesized from cDNA are presented
L, Birnbaumer, J, Abramowitz, A M, Brown
openaire +2 more sources
Lentiviral Effector Pathways of TRIM Proteins
DNA and Cell Biology, 2014The human tripartite motif (TRIM) family, composed of more than 77 members, encompasses an emerging group of innate antiviral factors. Most TRIM proteins are characterized by being E3 ubiquitin ligases, but also engage in specific interactions with a variety of cellular and viral partners.
Filippo, Turrini +2 more
openaire +2 more sources
Death Effector Domain-Containing Proteins
Cellular and Molecular Life Sciences, 2008Death effector domains (DEDs) are protein-protein interaction structures that are found in proteins that regulate a variety of signal transduction pathways. DEDs are a part of the larger family of Death Domain structures that have been primarily described in the control of programmed cell death.
M Gudur, Valmiki, J W, Ramos
openaire +2 more sources
Science's STKE, 2005
This Teaching Resource provides lecture notes and slides for a class covering two aspects of G protein–mediated signaling and is part of the course "Cell Signaling Systems: A Course for Graduate Students." The lecture begins with a discussion of the regulation of receptor-G protein coupling and then proceeds to describe the specificity of the response ...
openaire +1 more source
This Teaching Resource provides lecture notes and slides for a class covering two aspects of G protein–mediated signaling and is part of the course "Cell Signaling Systems: A Course for Graduate Students." The lecture begins with a discussion of the regulation of receptor-G protein coupling and then proceeds to describe the specificity of the response ...
openaire +1 more source
Interactions between Ras proteins and their effectors
Current Opinion in Biotechnology, 1996Abstract In the field of Ras-related GTP-binding proteins, the past two years have seen significant advances in the molecular characterization of their putative effectors/downstream targets.
McCormick, F., Wittinghofer, A.
openaire +3 more sources
Toxoplasma protein export and effector function
Nature MicrobiologyToxoplasma gondii is a single-celled eukaryotic parasite with a considerable host range that must invade the cells of warm-blooded hosts to survive and replicate. The challenges and opportunities that such a strategy represent have been met by the evolution of effectors that are delivered into host cells, counter host defences and co-opt host cell ...
Simona Seizova +3 more
openaire +3 more sources