Results 121 to 130 of about 9,881 (141)
Some of the next articles are maybe not open access.
Mechanism of efferocytosis in atherosclerosis
Journal of Molecular MedicineAtherosclerosis (AS) is a chronic inflammatory vascular disease that occurs in the intima of large and medium-sized arteries with the immune system's involvement. It is a common pathological basis for high morbidity and mortality of cardiovascular diseases.
Li-Xia Shu +4 more
openaire +2 more sources
The Tim gene family in efferocytosis
Genes & Genomics, 2020One of the key features of the plasma membrane is the asymmetrical distribution of phospholipids across it. Especially, phosphatidylserine (PS) exclusively locates on its inner leaflet. Thus, the exposure of PS on the surface of cells could function as a signal initiating various cellular processes such as phagocytosis of apoptotic cells called ...
Deokhwan Kim +4 more
openaire +2 more sources
Annual Review of Cell and Developmental Biology, 2017
In metazoans, removal of cells in situ is involved in larval maturation, metamorphosis, and embryonic development. In adults, such cell removal plays a role in the homeostatic maintenance of cell numbers and tissue integrity as well as in the response to cell injury and damage.
openaire +2 more sources
In metazoans, removal of cells in situ is involved in larval maturation, metamorphosis, and embryonic development. In adults, such cell removal plays a role in the homeostatic maintenance of cell numbers and tissue integrity as well as in the response to cell injury and damage.
openaire +2 more sources
The Role of Extracellular Vesicles in Efferocytosis
Mini-Reviews in Medicinal ChemistryAbstract: Efferocytosis is the physiological process of phagocytic clearance of apoptotic cells by both professional phagocytic cells, such as macrophages, and non-professional phagocytic cells, such as epithelial cells. This process is crucial for maintaining tissue homeostasis in normal physiology.
Susan, Panahi +7 more
openaire +2 more sources
Macrophage cannibalism: efferocytosis in atherosclerosis
Current Opinion in LipidologyPurpose of review This review explores the evolving understanding of efferocytosis – the clearance of dead or dying cells by phagocytes – in the context of atherosclerosis. It highlights recent discovers in cell death modalities, impaired clearance mechanisms and emerging therapeutic strategies aimed at ...
Amy A, Baxter +2 more
openaire +2 more sources
Insights of efferocytosis in normal and pathological pregnancy
American Journal of Reproductive Immunology, 2019AbstractEfferocytosis, which is known as the phagocytic clearance of dying cells by professional as well as non‐professional phagocytes, including a great number of intracellular/extracellular factors and signals, is interrelated with the immune system, contributing to local and systemic homeostasis, especially in tissues with high constitutive rates ...
Yan‐Ran Sheng +8 more
openaire +2 more sources
Efferocytosis in inflammatory bone disorders
Trends in Pharmacological SciencesEfferocytosis, the clearance of apoptotic cells (ACs) by phagocytes, is crucial for bone homeostasis and immune balance. This tightly regulated process depends on molecular markers such as phosphatidylserine on ACs and MERTK on phagocytes. In the bone microenvironment, multiple cell types participate in efferocytosis, including osteal macrophages ...
Linlin, Wen +4 more
openaire +2 more sources
Drugging the efferocytosis process: concepts and opportunities
Nature Reviews Drug Discovery, 2022Kodi S Ravichandran
exaly
Efferocytosis induces macrophage proliferation to help resolve tissue injury
Cell Metabolism, 2021Brennan D Gerlach +2 more
exaly
Metabolic adaptation supports enhanced macrophage efferocytosis in limited-oxygen environments
Cell Metabolism, 2023Waleska Saitz Rojas, Justin S A Perry
exaly