Results 61 to 70 of about 5,135,675 (370)

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Positive Impacts on Student Self-Efficacy from an Introductory Physics for Life Science Course Using the Team-Based Learning Pedagogy [PDF]

arXiv, 2020
We present the impact on student self-efficacy of an introductory physics for life-science students course taught using a Team-Based Learning pedagogy. We measured self-efficacy using the validated quantitative Sources of Self-Efficacy in Science Courses - Physics, SOSESC-P, survey developed by Fencl and Scheel.
arxiv  

Self-Efficacy and Academic Motivation

, 2002
: Academic motivation is discussed in terms of self-efficacy, an individual's judgments of his or her capabilities to perform given actions. After presenting an overview of self-efficacy theory, I contrast self-efficacy with related constructs (perceived
D. Schunk
semanticscholar   +1 more source

Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction.

New England Journal of Medicine, 2019
BACKGROUND Experimental and clinical evidence support the role of inflammation in atherosclerosis and its complications. Colchicine is an orally administered, potent antiinflammatory medication that is indicated for the treatment of gout and pericarditis.
J. Tardif, S. Kouz, D. Waters, O. Bertrand, R. Diaz, A. Maggioni, F. Pinto, R. Ibrahim, H. Gamra, G. Kiwan, C. Berry, J. López-Sendón, P. Ostadal, W. Koenig, D. Angoulvant, J. Grégoire, M. Lavoie, M. Dubé, D. Rhainds, Mylène Provencher, L. Blondeau, Andreas Orfanos, P. L'allier, M. Guertin, F. Roubille   +24 more
semanticscholar   +1 more source

Phase 3 Safety and Efficacy of AZD1222 (ChAdOx1 nCoV-19) Covid-19 Vaccine

New England Journal of Medicine, 2021
Background The safety and efficacy of the AZD1222 (ChAdOx1 nCoV-19) vaccine in a large, diverse population at increased risk for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the United States, Chile, and Peru has not been ...
A. Falsey, M. Sobieszczyk, I. Hirsch, Stephanie Sproule, M. Robb, L. Corey, K. Neuzil, William W Hahn, Julie Hunt, M. Mulligan, C. Mcevoy, E. Dejesus, Michael Hassman, S. Little, B. Pahud, A. Durbin, P. Pickrell, E. Daar, L. Bush, Joel Solis, Quito Osuna Carr, Temitope Oyedele, S. Buchbinder, J. Cowden, Sergio L Vargas, Alfredo Guerreros Benavides, R. Call, M. Keefer, B. Kirkpatrick, J. Pullman, T. Tong, Margaret Brewinski Isaacs, David C. Benkeser, H. Janes, M. Nason, Justin A. Green, E. Kelly, Jill Maaske, N. Mueller, Kathryn Shoemaker, Therese Takas, Richard P. Marshall, M. Pangalos, T. Villafana, Antonio Gonzalez-Lopez   +44 more
semanticscholar   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

The Causal Efficacy of Consciousness [PDF]

Entropy, 2020
Mental causation is vitally important to the integrated information theory (IIT), which says consciousness exists since it is causally efficacious. While it might not be directly apparent, metaphysical commitments have consequential entailments concerning the causal efficacy of consciousness.
Matthew Owen, Matthew Owen
openaire   +4 more sources

Physiological and pharmacological features of the non-saponin components in Korean Red Ginseng

Journal of Ginseng Research, 2020
Panax ginseng, a medicinal plant, has been used as a blood-nourishing tonic for thousands of years in Asia, including Korea and China. P. ginseng exhibits adaptogen activity that maintains homeostasis by restoring general biological functions and non ...
Sun Hee Hyun, Sung Won Kim, Hwi Won Seo, Soo Hyun Youn, Jong Soo Kyung, Yong Yook Lee, Gyo In, Chae-Kyu Park, Chang-Kyun Han   +8 more
doaj  

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

The commensal microbiome is associated with anti–PD-1 efficacy in metastatic melanoma patients

Science, 2018
Good bacteria help fight cancer Resident gut bacteria can affect patient responses to cancer immunotherapy (see the Perspective by Jobin). Routy et al. show that antibiotic consumption is associated with poor response to immunotherapeutic PD-1 blockade ...
Vyara Matson, Jessica Fessler, R. Bao, Tara Chongsuwat, Y. Zha, M. Alegre, J. Luke, T. Gajewski   +7 more
semanticscholar   +1 more source