Results 91 to 100 of about 7,737,786 (360)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Impact of Electric Vehicles Consumption on Energy Efficient and Self-Sufficient Performance in Building: A Case Study in the Brazilian Amazon Region

Energies
The growth of electric vehicles (EVs) and their integration into existing and future buildings bring new considerations for energy efficiency (EE) and balance when combined with renewable energy.
Ana Carolina Dias Barreto de Souza, Filipe Menezes de Vasconcelos, Gabriel Abel Massunanga Moreira, João Victor dos Reis. Alves, Jonathan Muñoz Tabora, Maria Emília de Lima Tostes, Carminda Célia Moura de Moura Carvalho, Andreia Antloga do Nascimento   +7 more
doaj   +1 more source

Semi‐Transparent Tandem Organic Solar Cells with 90% Internal Quantum Efficiency [PDF]

, 2012
Zheng Tang, Zandra George, Zaifei Ma, Jonas Bergqvist, Kristofer Tvingstedt, Koen Vandewal, Ergang Wang, L. Mattias Andersson, Mats R. Andersson, Fengling Zhang, Olle Inganäs   +10 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Aluminum fumarate MOF/PVDF hollow fiber membrane for enhancement of water flux and thermal efficiency in direct contact membrane distillation [PDF]

, 2019
Dongjian Cheng, Lihua Zhao, Na Li, Stefan J. D. Smith, Dongyun Wu, Jianhua Zhang, Derrick Ng, Chunrui Wu, Marta Rubio‐Martínez, M.P. Batten, Zongli Xie   +10 more
openalex   +1 more source

Efficiently learning efficient programs

, 2017
Discovering efficient algorithms is central to computer science. In this thesis, we aim to discover efficient programs (algorithms) using machine learning. Specifically, we claim we can efficiently learn programs (Claim 1), and learn efficient programs (Claim 2).
openaire   +3 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Exploration and case analysis of treatment processes and reuse pathways for industrial brine wastewater in China

Water Cycle
Treatment of industrial brine wastewater, which is characterized by multiple sources and complex water quality, poses significant challenges. Brine separation technology can effectively address the difficulties in brine wastewater treatment while ...
Jialin Liu, Xue Bai, Yan Bai
doaj   +1 more source

Increasing Energy Efficiency Based on the Kaizen Approach [PDF]

, 2023
Armenia Androniceanu, I. Enache, Elena-Narcisa Valter, Florinfelix Raduica   +3 more
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source