Results 51 to 60 of about 6,001,435 (308)
A Review of the DAC Evaluation Criteria: Upgrading Efficiency
Journal of MultiDisciplinary Evaluation, 2020 Background: Efficiency has remained for long time the Cinderella of evaluation practice. According to several meta-evaluations only a small number of evaluations include robust and meaningful assessments in this field. Purpose: Following the review of
Joaquín de la Concha González
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
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Electroneurophysiological criteria of efficiency of pathogenetic therapy in diabetic polyneuropathy. [PDF]
Ķazaķstannyṇ Klinikalyķ Medicinasy, 2016 Purpose: to estimate efficiency of pathogenetic therapy of diabetic polyneuropathy with including of benfotiaminby means of an electroneuromyography.
Lubov Kuzina, Gulnaz Kaishibayeva
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Pharmacoeconomics of spastic cerebral palsy
Регуляторные исследования и экспертиза лекарственных средств, 2018 Cerebral palsy (CP) is one of the most widespread and socially significant neurological diseases that affect both various aspects of physical and psychoverbal development of children since birth and stages of their personal development and adaptation in ...
R. I. Yagudina +3 more
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Multi-Criteria Evaluation of Efficiency in Fish Processing
Environmental and Climate Technologies, 2020 Carbon neutrality has become a goal of European Union countries as they held agreement on the European Green Deal; the goal needs to be achieved by 2050.
Dreimanis Karlis +3 more
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Efficiency Criteria and Risk Aversion: An Empirical Evaluation [PDF]
Journal of Agricultural and Applied Economics, 1988 AbstractA conceptual link among mean-variance (EV), stochastic dominance (SD), mean-risk (ET), and Gini mean difference (EG) is established for determining risk efficient decision sets. The theoretical relations among the various efficiency criteria are then empirically demonstrated with a soybean and wheat double-crop simulation model.
Wetzstein, Michael E. +3 more
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
JUSTIFICATION OF CRITERIA FOR ROPEWAYS ENERGY EFFICIENCY
Nauka ta progres transportu, 2019 Purpose. The article is aimed to form and justify the energy efficiency indicators of ropeways of traditional design and ropeways with self-propelled wagons based on the determination and comparison of their values.
S. V. Raksha +2 more
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Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
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