Results 91 to 100 of about 1,045,667 (319)

Resilient Agrifood System Science Group: Evaluation Report [PDF]

open access: yes
The CGIAR 2030 Research and Innovation Strategy sets priorities to deliver solutions for development through 33 initiatives across three interlinked action areas: Systems Transformation, Resilient Agrifood Systems (RAFS), and Genetic Innovation. The RAFS
Fakoya, K.   +4 more
core  

Investment Project Efficiency Evaluation [PDF]

open access: yesInterdisciplinary Management Research, 2006
Financial efficiency of investment project is being evaluated in this paper. It is showed that the net present value function is constant and that quota value is equal to c0 when i converges to the infinite. Optimal rates i are analyzed in certain cases and everything is illustrated through examples.
Miljenko Crnjac, Dominika Crnjac
openaire   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Strategic Alignment of Technological Innovation for Sustainable Development: Efficiency Evaluation and Spatial Analysis in China’s Advanced Manufacturing Industry

open access: yesSystems
Technological innovation is essential to promoting sustainable development in emerging economies as it drives regional coordination and industry upgrading.
Zhenghan Chen   +3 more
doaj   +1 more source

Resilient Agrifood Systems Science Group: Evaluation Report, Annexes [PDF]

open access: yes
The CGIAR 2030 Research and Innovation Strategy sets priorities to deliver solutions for development through 33 initiatives across three interlinked action areas: Systems Transformation, Resilient Agrifood Systems (RAFS), and Genetic Innovation. The RAFS
Fakoya, K.   +4 more
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Methodologies for Assessment of Building's Energy Efficiency and Conservation: A Policy-Maker View [PDF]

open access: yes
Recent global peer-review reports have concluded on importance of buildings in tacking the energy security and climate change challenges. To integrate the buildings energy efficiency into the policy agenda, significant research efforts have been recently
Aleksandra Novikova
core  

Optimized Regression for Efficient Function Evaluation

open access: yesIEEE Transactions on Image Processing, 2012
In many applications of regression, one is concerned with the efficiency of the estimated function in addition to the accuracy of the regression. For efficiency, it is common to represent the estimated function as a rectangular lattice of values-a lookup table (LUT)-that can be linearly interpolated for any needed value. Typically, a LUT is constructed
Eric K. Garcia   +2 more
openaire   +2 more sources

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