Results 81 to 90 of about 9,271,499 (307)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Annual corporate evaluation report 2010 [PDF]
, 2010 French version available in IDRC Digital Library: Rapport annuel sur l'évaluation 2010This report presents an in-depth analysis of selected evaluation topics, and notes the importance of the IDRC’s efforts in searching for improved approaches to ...
IDRC. Evaluation Unit
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FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Evaluation of Program Efficiency [PDF]
Public Health Reports (1896-1970), 1968 O L, Deniston +3 more
openaire +2 more sources
Evaluating the Efficiency of Blockchains in IoT with Simulations
Proceedings of the 2nd International Conference on Internet of Things, Big Data and Security, 2017 As blockchain technology has gained popularity in many different application areas, there is a need to have tools for prototyping and evaluating various ways of applying blockchains. One interesting venue where this type of evaluation is very important is Internet of Things (IoT).
Kreku, Jari +4 more
openaire +4 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Report of the Energy Efficiency Board. 2011.
, 2011 Annual; Began with 2010.; At head of title: Connecticut Energy Efficiency ...
Connecticut. Energy Efficiency Board.
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Optimized Regression for Efficient Function Evaluation
IEEE Transactions on Image Processing, 2012 In many applications of regression, one is concerned with the efficiency of the estimated function in addition to the accuracy of the regression. For efficiency, it is common to represent the estimated function as a rectangular lattice of values-a lookup table (LUT)-that can be linearly interpolated for any needed value. Typically, a LUT is constructed
Eric K. Garcia +2 more
openaire +3 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Report of the Energy Efficiency Board. 2010.
, 2010 Annual; Began with 2010.; At head of title: Connecticut Energy Efficiency ...
Connecticut. Energy Efficiency Board.
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