Results 171 to 180 of about 1,045,667 (319)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Universal Viral Screening of Patients with Newly Diagnosed Cancer in the United States: A Cost-efficiency Evaluation. [PDF]

Cancer Res Commun, 2023
Vaidya R, Unger JM, Loomba R, Hwang JP, Chugh R, Tincopa MA, Arnold KB, Hershman DL, Ramsey SD.   +8 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Bridging heat-flow and guarded-heater methods for thermoelectric module efficiency evaluation. [PDF]

iScience
Amagai Y, Okawa K, Funahashi R, Yamamoto A, Ohta M.   +4 more
europepmc   +1 more source

Subjective Efficiency Evaluation after Maxillomandibular Advancement Surgery in Obstructive Sleep Apnea Patients. [PDF]

J Clin Med, 2023
Kuik K, Tan ML, Ho JTF, Lindeboom JAH, de Lange J.   +4 more
europepmc   +1 more source

Methodological Solutions for Evaluation of Land Use Efficiency

Land use efficiency can be evaluated by using both selected methods and developed system of appropriate indicators. This system is created and applicable for analysis the socio-economic and environmental aspects of the dynamic changes of land use ...
Auziņš, Armands
core  

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Research on the application of refined operating room turnover efficiency in cross-hospital operating room efficiency evaluation. [PDF]

BMC Surg
Zhang C, Gong R, Yan F, Liu Y, Zang L, Pang W, Shu Y.   +6 more
europepmc   +1 more source

Scientific research input and output efficiency evaluation of universities in Chengdu-Chongqing economic circle based on data envelopment analysis. [PDF]

PLoS One, 2023
Wang C, Zeng J, Zhong H, Si W.
europepmc   +1 more source

In measuring aggregate"social efficiency" [PDF]

Cross-country comparisons of social indicators controlling for income and/or social spending have been widely used to measure and explain"social efficiency"analogously to"technical efficiency"in production.
Ravallion, Martin
core