Results 61 to 70 of about 3,292,414 (307)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

A Flexible Multi-Mechanism Market Model for Air Conditioning Users in Electricity Market: Design and Application

IEEE Access
With the continuous growth of electricity demand, optimizing load management strategies has become a crucial approach for alleviating the pressure on power supply.
Chupeng Xiao, Zhuofan Tang, Suoyue Wang, Kui Wang, Rui Xiang, Xiaojing Li   +5 more
doaj   +1 more source

DESIGN MODELING OF A UNIVERSITY’S COMPREHENSIVE-INTEGRATED SECURITY SYSTEM

Интеграция образования, 2017
Introduction: the safety of higher education institutions is considered to be of great importance nowadays. Security challenges need to be addressed through a comprehensive and integrative approach.
Marina V. Dulyasova, Valeriy V. Markin
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Regional Differences and Dynamic Changes in Sea Use Efficiency in China

Journal of Marine Science and Engineering, 2022
This study aims to identify the overall level of China’s sea use efficiency (SUE) from 2006 to 2018 as well as regional differences and dynamic changes The super-efficiency weighted slacks-based measure (Super-WSBM) model and the global Malmquist ...
Qian Zhang, Xuan Yu
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Methodological problems with evaluating change efficiency

Ekonomia i Prawo, 2018
Motivation: Changes result from a turbulent environment and internal situation of an organization. Rarely do changes happen spontaneously, usually they stem from decisions consciously shaped and taken by the management.
Jerzy Paszkowski
doaj   +1 more source

Fight against COVID-19: a global efficiency evaluation based on contagion control and medical treatment

Journal of Applied Research on Industrial Engineering, 2020
There have been several major global outbreaks during the past decades, with the latest being the worst. The COVID-19 pandemic has infected hundreds of thousands and killed thousands in the world affecting most countries in around the globe.
Hadi Shirouyehzad, Javid Jouzdani, Mazdak Khodadadi Karimvand   +2 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source